通过Mo(3+)掺杂增强NaYF4:Yb/Er纳米晶的上转换发光及其在生物成像中的应用

Enhancing upconversion luminescence of NaYF4:Yb/Er nanocrystals by Mo(3+) doping and their application in bioimaging.

作者信息

Yin Dongguang, Wang Chengcheng, Ouyang Juan, Song Kailin, Liu Bing, Cao Xianzhang, Zhang Lu, Han Yanlin, Long Xie, Wu Minghong

机构信息

School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.

出版信息

Dalton Trans. 2014 Aug 21;43(31):12037-43. doi: 10.1039/c4dt00172a.

DOI:10.1039/c4dt00172a

PMID:24979546

Abstract

Enhancement of upconversion luminescence is imperative for the applications of upconversion nanocrystals (UCNs). In this work, we investigated the upconversion luminescence enhancement of NaYF4:Yb/Er by Mo(3+) ion doping. It was found that the upconversion luminescence intensities of the green and red emissions of UCNs co-doped with 10 mol% Mo(3+) ions were enhanced by 6 and 8 times, respectively. This enhancement offers a potential increase in the overall detectability of upconversion nanocrystals. HeLa cell imaging using NaYF4:Yb/Er/Mo as luminescent probes showed bright upconversion fluorescence. Moreover, the Mo(3+) doping endowed the UCNs with excellent paramagnetic behavior. It is expected that the as-prepared UCNs with a high upconversion luminescence and excellent paramagnetic properties could be promising bi-functional nanoprobes for sensitive multi-modal bioimaging and other optical applications.

摘要

上转换发光的增强对于上转换纳米晶体（UCNs）的应用至关重要。在这项工作中，我们研究了通过Mo(3+)离子掺杂来增强NaYF4:Yb/Er的上转换发光。结果发现，共掺杂10 mol% Mo(3+)离子的UCNs的绿色和红色发射的上转换发光强度分别提高了6倍和8倍。这种增强有望提高上转换纳米晶体的整体可检测性。使用NaYF4:Yb/Er/Mo作为发光探针的HeLa细胞成像显示出明亮的上转换荧光。此外，Mo(3+)掺杂赋予了UCNs优异的顺磁行为。预计所制备的具有高上转换发光和优异顺磁性能的UCNs有望成为用于灵敏多模态生物成像和其他光学应用的双功能纳米探针。