Harjacek Miroslav
Reumatizam. 2013;60(2):30-4.
Childhood vasculitis is a challenge for pediatric rheumatologists. It is multisystem in nature and often requires integrated care from multiple subspecialties, including rheumatology, dermatology, cardiology, nephrology, neurology, and gastroenterology. Vasculitis is defined as the presence of inflammation in the blood vessel wall. The site of vessel involvement, size of the affected vessels, extent of vascular injury, and underlying pathology determine the disease phenotype and severity. This article explores the classification and general features of pediatric vasculitides, with detailed analisys of the two most common vasculitides: Henoch-Schönlein purpura and Kawasaki disease.
儿童血管炎对儿科风湿病学家来说是一项挑战。它本质上是多系统疾病,通常需要包括风湿病学、皮肤病学、心脏病学、肾脏病学、神经病学和胃肠病学等多个亚专业的综合治疗。血管炎被定义为血管壁存在炎症。血管受累部位、受累血管大小、血管损伤程度以及潜在病理决定了疾病的表型和严重程度。本文探讨了儿童血管炎的分类和一般特征,并对两种最常见的血管炎:过敏性紫癜和川崎病进行了详细分析。