基于伴侣的HIV干预与预防研究的系统评价：优势、差距及未来方向
Systematic review of couple-based HIV intervention and prevention studies: advantages, gaps, and future directions.
作者信息
Jiwatram-Negrón Tina, El-Bassel Nabila
机构信息
School of Social Work, Columbia University, 1255 Amsterdam Avenue, Room 825, New York City, NY, 10027, USA,
出版信息
AIDS Behav. 2014 Oct;18(10):1864-87. doi: 10.1007/s10461-014-0827-7.
Abstract
We conducted a systematic review of couple-based HIV biobehavioral (skills-building, VCT, and adherence) and biomedical (ART, circumcision) prevention and intervention studies designed to reduce sexual- and drug-risk behaviors and HIV transmission and acquisition. Of the 11,162 papers identified in the search, 93 peer-reviewed papers met the inclusion criteria and yielded a total of 33 studies conducted globally. Biobehavioral couple-based prevention and intervention studies have been efficacious in reducing sexual- and drug-risk behaviors, increasing access to HIV testing and care, and improving adherence. Biomedical couple-based studies were found to reduce HIV incidence among HIV-negative sex partners and viral load among HIV-positive partners. Despite much progress, couple-based HIV prevention and intervention studies remain limited; a number of methodological gaps exist and studies focusing on MSM, people who inject drugs, and sex workers are scarce.
摘要
我们对基于伴侣的HIV生物行为（技能培养、自愿咨询检测及依从性）和生物医学（抗逆转录病毒治疗、包皮环切术）预防及干预研究进行了系统综述，这些研究旨在减少性和毒品风险行为以及HIV传播与感染。在检索到的11162篇论文中，93篇经过同行评审的论文符合纳入标准，共产生了全球范围内开展的33项研究。基于伴侣的生物行为预防及干预研究在减少性和毒品风险行为、增加HIV检测及治疗可及性以及提高依从性方面已见成效。基于伴侣的生物医学研究被发现可降低HIV阴性性伴侣中的HIV发病率以及HIV阳性伴侣中的病毒载量。尽管取得了很大进展，但基于伴侣的HIV预防及干预研究仍然有限；存在一些方法学上的差距，且针对男男性行为者、注射吸毒者和性工作者的研究很少。
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2
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Sex Transm Infect. 2013 Dec;89(8):620-7. doi: 10.1136/sextrans-2013-051135. Epub 2013 Aug 5.
3
Health, trust, or "just understood": explicit and implicit condom decision-making processes among black, white, and interracial same-sex male couples.健康、信任还是“心照不宣”：黑人群体、白人群体和跨种族男同性恋群体在决定使用避孕套时的显性和隐性因素。
Arch Sex Behav. 2014 May;43(4):697-706. doi: 10.1007/s10508-013-0146-5. Epub 2013 Aug 3.
4
The changing epidemiology of HIV in 2013.2013 年 HIV 的流行病学变化。
Curr Opin HIV AIDS. 2013 Jul;8(4):306-10. doi: 10.1097/COH.0b013e328361f53a.
5
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6
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7
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