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治疗时间——从入院到球囊扩张时间并非一切。

Time to treatment-door-to-balloon time is not everything.

作者信息

Terkelsen C J

机构信息

Department of cardiology B, Aarhus University Hospital in Skejby, Skejby, Denmark,

出版信息

Herz. 2014 Sep;39(6):672-6. doi: 10.1007/s00059-014-4125-y.

DOI:10.1007/s00059-014-4125-y
PMID:24980984
Abstract

International guidelines for the management of patients with ST-elevation myocardial infarction (STEMI) recommend various performance measures to monitor the quality of STEMI systems of care. Door-to-balloon (D2B) time (arrival at hospital to percutaneous coronary intervention, PCI) and overall health care system delay (first medical contact to reperfusion) are acknowledged as valuable performance measures when treating patients with primary percutaneous coronary intervention (PPCI). However, there is confusion regarding the exact definition of these performance measures, and moreover system delay and PCI-related delay (the extra delay acceptable to perform PPCI instead of fibrinolysis) are often used synonymously, which add confusion when considering reperfusion strategy. The present paper calls for a consensus regarding the use and definition of objective performance measures when treating patients with STEMI, and exemplifies why it is insufficient just to focus on D2B time.

摘要

ST段抬高型心肌梗死(STEMI)患者管理的国际指南推荐了各种绩效指标,以监测STEMI护理系统的质量。门球时间(从到达医院至经皮冠状动脉介入治疗,PCI)和整体医疗系统延迟(首次医疗接触至再灌注)在治疗接受直接经皮冠状动脉介入治疗(PPCI)的患者时,被公认为是有价值的绩效指标。然而,这些绩效指标的确切定义存在混淆,此外,系统延迟和PCI相关延迟(进行PPCI而非溶栓治疗可接受的额外延迟)经常被同义使用,这在考虑再灌注策略时增加了混淆。本文呼吁在治疗STEMI患者时,就客观绩效指标的使用和定义达成共识,并举例说明仅关注门球时间为何是不够的。

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Time to treatment-door-to-balloon time is not everything.治疗时间——从入院到球囊扩张时间并非一切。
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2
Quality of care in primary percutaneous coronary intervention for acute ST-segment -elevation myocardial infarction: Gulf RACE 2 experience.急性ST段抬高型心肌梗死直接经皮冠状动脉介入治疗的医疗质量:海湾地区RACE 2研究经验
Ann Saudi Med. 2014 Nov-Dec;34(6):482-7. doi: 10.5144/0256-4947.2014.482.

本文引用的文献

1
Diagnostic performance and system delay using telemedicine for prehospital diagnosis in triaging and treatment of STEMI.远程医疗在 ST 段抬高型心肌梗死分诊和治疗中的院前诊断中的诊断性能和系统延迟。
Heart. 2014 May;100(9):711-5. doi: 10.1136/heartjnl-2013-304576. Epub 2014 Mar 17.
2
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2012年欧洲心脏病学会ST段抬高型心肌梗死指南与再灌注治疗:基于证据的推荐意见,确保患者得到最佳管理。
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4
2012 ESC STEMI guidelines and reperfusion therapy: Evidence base ignored, threatening optimal patient management.2012年欧洲心脏病学会ST段抬高型心肌梗死指南与再灌注治疗:忽视证据基础,危及患者的最佳治疗管理。
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5
Timely PCI for STEMI--still the treatment of choice.ST段抬高型心肌梗死的及时经皮冠状动脉介入治疗——仍然是首选治疗方法。
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6
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.ST 段抬高型心肌梗死的溶栓治疗或直接经皮冠状动脉介入治疗。
N Engl J Med. 2013 Apr 11;368(15):1379-87. doi: 10.1056/NEJMoa1301092. Epub 2013 Mar 10.
7
ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation.ST段抬高型急性心肌梗死患者管理的欧洲心脏病学会指南
Eur Heart J. 2012 Oct;33(20):2569-619. doi: 10.1093/eurheartj/ehs215. Epub 2012 Aug 24.
8
Primary percutaneous coronary intervention as a national reperfusion strategy in patients with ST-segment elevation myocardial infarction.直接经皮冠状动脉介入治疗作为 ST 段抬高型心肌梗死患者的国家再灌注策略。
Circ Cardiovasc Interv. 2011 Dec 1;4(6):570-6. doi: 10.1161/CIRCINTERVENTIONS.111.962787. Epub 2011 Nov 9.
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Benefit of transferring ST-segment-elevation myocardial infarction patients for percutaneous coronary intervention compared with administration of onsite fibrinolytic declines as delays increase.与在现场使用纤溶酶相比,ST 段抬高型心肌梗死患者接受经皮冠状动脉介入治疗的获益随着时间的延迟而减少。
Circulation. 2011 Dec 6;124(23):2512-21. doi: 10.1161/CIRCULATIONAHA.111.018549. Epub 2011 Nov 7.
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System delay and mortality among patients with STEMI treated with primary percutaneous coronary intervention.直接经皮冠状动脉介入治疗治疗的 STEMI 患者的系统延迟与死亡率。
JAMA. 2010 Aug 18;304(7):763-71. doi: 10.1001/jama.2010.1139.