对两株在DNA修复和遗传不稳定性方面存在缺陷的卡特利链霉菌突变体进行分离和研究。
Isolation and study of two mutants of Streptomyces cattleya affected in DNA repair and genetic instability.
作者信息
Hromic A, Kirby R
机构信息
Department of Microbiology, University of Stellenbosch, South Africa.
出版信息
FEMS Microbiol Lett. 1989 Jan 15;48(2):139-43. doi: 10.1111/j.1574-6968.1989.tb03288.x.
Abstract
Two mutants of Streptomyces cattleya affecting DNA repair were isolated. These mutants were analysed using spore survival curves and phage reactivation curves in the presence and absence of caffeine and arsenite. Two DNA repair systems (uvr1 and uvr2) were identified, the latter of which seems to influence genetic instability.
摘要
分离出了两株影响DNA修复的卡特利链霉菌突变体。利用孢子存活曲线和噬菌体复活曲线，在有和没有咖啡因及亚砷酸盐存在的情况下对这些突变体进行了分析。鉴定出了两个DNA修复系统（uvr1和uvr2），其中后者似乎会影响遗传不稳定性。
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