Koyuncu Hakan, Serefoglu Ege Can, Karacay Safak, Ozdemir Ahmet Tunc, Kalkan Mehmet, Yencilek Faruk
Department of Urology, Yeditepe University School of Medicine, Istanbul, Turkey.
Department of Urology, Tulane University School of Medicine, New Orleans, USA.
Cent European J Urol. 2014;67(1):74-8. doi: 10.5173/ceju.2014.01.art16. Epub 2014 Apr 17.
Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (ME) is nocturnal bed wetting, without any daytime symptoms. Recent clinical studies report an association between lifelong PE and ME. The purpose of this study was to compare the intravaginal ejaculatory time (IELT) between lifelong PE in men with and without ME. The goal was to determine if there is an association between the severity of ME and of IELT.
A total of 137 men with lifelong PE were included in this study. Subjects were asked if they had childhood ME. The characteristics and mean IELTs of patients with and without ME were compared using the student's t-test, and the correlation between severity of ME and IELT was assessed with trend test.
Of the 137 lifelong PE patients, 57 reported ME. There was a strong negative correlation in patients with ME between the severity of enuresis and IELT, with IELT being shorter in patients with severe ME.
A strong correlation between IELT and the severity of ME suggests a common underlying mechanism. Further studies are required to confirm these findings and elucidate the exact pathophysiology.
早泄(PE)是最常见的男性性功能障碍。单纯性遗尿(ME)是夜间尿床,无任何日间症状。近期临床研究报告了终身性早泄与单纯性遗尿之间的关联。本研究的目的是比较有和没有单纯性遗尿的男性终身性早泄患者的阴道内射精潜伏期(IELT)。目标是确定单纯性遗尿的严重程度与阴道内射精潜伏期之间是否存在关联。
本研究共纳入137例终身性早泄男性。询问受试者是否有儿童期单纯性遗尿。使用学生t检验比较有和没有单纯性遗尿患者的特征及平均阴道内射精潜伏期,并通过趋势检验评估单纯性遗尿严重程度与阴道内射精潜伏期之间的相关性。
137例终身性早泄患者中,57例报告有单纯性遗尿。在有单纯性遗尿的患者中,遗尿严重程度与阴道内射精潜伏期呈强烈负相关,重度单纯性遗尿患者的阴道内射精潜伏期较短。
阴道内射精潜伏期与单纯性遗尿严重程度之间的强相关性提示存在共同的潜在机制。需要进一步研究以证实这些发现并阐明确切的病理生理学机制。