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关于人类大脑皮质脊髓束映射与量化的一则注释

A note on the mapping and quantification of the human brain corticospinal tract.

作者信息

Keser Z, Yozbatiran N, Francisco G E, Hasan K M

机构信息

Department of Physical Medicine and Rehabilitation and TIRR Memorial Hermann NeuroRecovery Research Center, United States.

Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, TX, United States.

出版信息

Eur J Radiol. 2014 Sep;83(9):1703-5. doi: 10.1016/j.ejrad.2014.05.022. Epub 2014 May 27.

DOI:10.1016/j.ejrad.2014.05.022
PMID:24985340
Abstract

Several diffusion tensor imaging tractography (DTT) have been adopted to construct the living human brain corticospinal tract. In this Note, we applied method "A" as recently described and used by "Lin CC, Tsai MY, Lo YC, et al. Reproducibility of corticospinal diffusion tensor tractography innormal subjects and hemiparetic stroke patients. Eur J Radiol 2013;82: e610-6." We compared the results obtained with method "A" with those obtained using an anatomy-guided method "B" on two healthy adults. We also quantified the results using tract volume, and corresponding fractional anisotropy, mean, and radial diffusivities. We demonstrate that accurate mapping and quantification of CST requires at least two regions of interest one at the level of the medulla oblongata, a second at the level of pons, this assures termination at the motor spine and contamination with cerebellar and sensory pathways.

摘要

几种扩散张量成像纤维束示踪法(DTT)已被用于构建活体人类大脑皮质脊髓束。在本报告中,我们应用了最近由“Lin CC、Tsai MY、Lo YC等人描述和使用的方法“A”。《皮质脊髓扩散张量纤维束示踪在正常受试者和偏瘫中风患者中的可重复性》。欧洲放射学杂志2013年;82:e610 - 6。我们在两名健康成年人身上将方法“A”获得的结果与使用解剖学引导方法“B”获得的结果进行了比较。我们还使用纤维束体积以及相应的分数各向异性、平均扩散率和径向扩散率对结果进行了量化。我们证明,准确绘制和量化皮质脊髓束至少需要两个感兴趣区域,一个在延髓水平,另一个在脑桥水平,这可确保在运动脊髓处终止并避免与小脑和感觉通路发生混淆。

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