Wang Cunchuan, Feng Zhiqi, Li Jinyi, Yang Wah, Zhai Hening, Choi Nim, Yang Jingge, Hu Youzhu, Pan Yunlong, Cao Guo
Department of General Surgery, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China,
Surg Endosc. 2015 Jan;29(1):192-201. doi: 10.1007/s00464-014-3658-8. Epub 2014 Jul 2.
The aim of this study was to evaluate the effect and cosmetic results of endoscopic thyroidectomy (ETE) via the areola approach for patients with thyroid diseases.
A total of 1,250 patients with thyroid diseases underwent ETE via the areola approach between April 2005 and January 2011. Of these, 898 were benign goiters, 260 were Graves' disease, 28 were secondary hyperthyroidism, and 64 were papillary carcinomas.
The surgery was successfully completed in 1,249 cases, and 1 case was converted to open surgery. The mean operation time, estimated blood loss, and hospital stay after surgery for patients with a goiter, hyperthyroidism, and papillary carcinoma were 94.4 min, 15.2 ml, 5.0 days, 97.9 min, 16.1 ml, 5.5 days, and 134.3 min, 18.6 ml, 6.4 days, respectively. Complications included 4 cases of postoperative bleeding, 1 case of transection of the recurrent laryngeal nerve (RLN) on one side, 7 cases of temporary RLN injury, 34 cases of transient hypocalcemia, 5 cases of skin bruising on the chest wall, and 1 case of subcutaneous infection in the neck. At 4.6-year (2.5-8 years) follow-up of 1,185 (94.8 %) patients, 3 patients with Graves' disease had recurrence of hyperthyroidism, and 4 patients with nodular goiter had recurrence of small nodules. Four patients had discomfort on swallowing, 4 patients had an abnormal sensation of skin traction on the neck and the chest, and 1 patient with scar diathesis had mild scar hyperplasia. A total of 876 patients were satisfied, 4 equivocal, and 0 unsatisfied with the cosmetic results.
ETE via the areola approach for patients with benign goiters, Graves' disease, secondary hyperthyroidism, and papillary carcinomas without metastasis to lateral cervical lymph nodes is an effective and safe procedure with excellent cosmetic results.
本研究旨在评估经乳晕入路内镜甲状腺切除术(ETE)对甲状腺疾病患者的疗效及美容效果。
2005年4月至2011年1月期间,共有1250例甲状腺疾病患者接受了经乳晕入路的ETE。其中,898例为良性甲状腺肿,260例为格雷夫斯病,28例为继发性甲状腺功能亢进,64例为乳头状癌。
1249例手术成功完成,1例转为开放手术。甲状腺肿、甲状腺功能亢进和乳头状癌患者的平均手术时间、估计失血量和术后住院时间分别为94.4分钟、15.2毫升、5.0天,97.9分钟、16.1毫升、5.5天,以及134.3分钟、18.6毫升、6.4天。并发症包括4例术后出血、1例一侧喉返神经切断、7例喉返神经暂时性损伤、34例短暂性低钙血症、5例胸壁皮肤瘀斑和1例颈部皮下感染。对1185例(94.8%)患者进行4.6年(2.5 - 8年)随访,3例格雷夫斯病患者出现甲状腺功能亢进复发,4例结节性甲状腺肿患者出现小结节复发。4例患者吞咽时有不适感,4例患者颈部和胸部有皮肤牵拉异常感,1例瘢痕体质患者有轻度瘢痕增生。共有876例患者对美容效果满意,4例态度模糊,0例不满意。
对于良性甲状腺肿、格雷夫斯病、继发性甲状腺功能亢进以及未发生侧颈淋巴结转移的乳头状癌患者,经乳晕入路的ETE是一种有效且安全的手术,美容效果极佳。