Zona Amerigo, Marcello Ida, Carere Mario, Soggiu Maria Eleonora, Falleni Fabrizio, Beccaloni Eleonora, Comba Pietro
Dipartimento ambiente e connessa prevenzione primaria, Istituto superiore di sanità, Roma.
Epidemiol Prev. 2014 Mar-Apr;38(2 Suppl 1):144-52.
SENTIERI Project evaluates the health impact of environmental exposures on residential population of National Priority Contaminated Sites (NPCSs). It takes into account a priori etiological hypotheses, based on the epidemiological evidence of an association between those exposures and selected diseases or causes of death. Building on the previous chapter, this one acts as a blueprint for future causal inferences based on scientific evidence relating to the health effects of exposure to specific pollutants present in the sites. In order to select the relevant pollutants, we make use of data concerning soil, aquifers, the food chain and the atmosphere. For each pollutant, we indicate cancer site and target organs, for non-neoplastic diseases, based on scientific assessment by international Agencies. We have chosen to focus on two sites: Brescia-Caffaro and Priolo. This method may conceivably be used by SENTIERI in the future to carry out more specific studies and provides the basis for a systematic analysis of contaminated sites.
SENTIERI项目评估环境暴露对国家重点污染场地（NPCSs）居住人口健康的影响。它考虑了先验病因假设，这些假设基于那些暴露与选定疾病或死亡原因之间关联的流行病学证据。基于上一章内容，本章作为未来因果推断的蓝图，该推断基于与场地中存在的特定污染物暴露对健康影响相关的科学证据。为了选择相关污染物，我们利用有关土壤、含水层、食物链和大气的数据。对于每种污染物，基于国际机构的科学评估，我们指出癌症部位和目标器官以及非肿瘤性疾病。我们选择聚焦于两个场地：布雷西亚 - 卡法罗和普廖洛。可以想象，SENTIERI未来可能会使用这种方法开展更具体的研究，并为污染场地的系统分析提供基础。
