[利用绒毛取样进行产前胎儿血型鉴定]

[Prenatal fetal blood group determination using chorionic villi biopsy].

作者信息

Kanhai H H, Gemke R J, Overbeeke M A, Bernini L F, Beverstock G C, Bennebroek Gravenhorst J

出版信息

Ned Tijdschr Geneeskd. 1989 Apr 22;133(16):819-21.

Abstract

The presence or absence of Rhesus D, c and Kell antigens on foetal red blood cells was determined in the first trimester of pregnancy on erythrocytes obtained by chorionic villi sampling. Pregnancies in 15 severely sensitized women (9 Rh D, 5 Kell and I Rh c) with a poor obstetric history and a partner heterozygous for the offending antigen were examined. A conclusive diagnosis could be made in 13 of the 15 cases studied.

摘要

在妊娠早期，通过绒毛取样获得的胎儿红细胞上，测定了恒河猴D、c和凯尔抗原的存在与否。对15名严重致敏女性（9名Rh D、5名凯尔和1名Rh c）的妊娠情况进行了检查，这些女性有不良产科病史，其伴侣为致病抗原的杂合子。在所研究的15例病例中，有13例可作出明确诊断。