Ishi Yukitomo, Nakayama Naoki, Kobayashi Hiroyuki, Yamaguchi Shigeru, Terasaka Shunsuke, Houkin Kiyohiro
Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Case Rep Neurol. 2014 May 27;6(2):139-43. doi: 10.1159/000362867. eCollection 2014 May.
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms arising from the gastrointestinal tract. The authors present a case of the successful removal of a metastatic GIST in the craniovertebral junction, using an occipital artery to posterior inferior cerebellar artery (OA-PICA) bypass. The patient is a 54-year-old male who underwent his first surgery for a small-bowel tumor at the age of 45 and was diagnosed with GIST. Nine years after his primary diagnosis, the patient suffered from severe neck pain. MRI demonstrated a large demarcated mass adjacent to the right atlas. The right vertebral artery (VA), completely engulfed by the tumor, showed a narrowing and ended in the PICA. Poor collateral blood supply in the right PICA territory was presumed. To prevent ischemic complications, an OA-PICA bypass was performed prior to the tumor resection. After the OA-PICA bypass, the tumor associated with the right VA was successfully removed, and the patient was discharged without any neurological deficits.
胃肠道间质瘤(GIST)是起源于胃肠道的罕见间叶性肿瘤。作者报告了一例成功切除颅颈交界区转移性GIST的病例,采用枕动脉至小脑后下动脉(OA-PICA)搭桥术。患者为54岁男性,45岁时因小肠肿瘤接受首次手术,被诊断为GIST。初次诊断9年后,患者出现严重颈部疼痛。MRI显示右侧寰椎旁有一个边界清晰的大肿块。右侧椎动脉(VA)完全被肿瘤包绕,显示狭窄并终止于小脑后下动脉。推测右侧小脑后下动脉区域的侧支血供较差。为预防缺血性并发症,在肿瘤切除术前进行了OA-PICA搭桥术。OA-PICA搭桥术后,与右侧椎动脉相关的肿瘤被成功切除,患者出院时无任何神经功能缺损。