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用于生物传感应用的杯型回音壁模式微腔阵列的大规模平行表面功能化。

Large-scale parallel surface functionalization of goblet-type whispering gallery mode microcavity arrays for biosensing applications.

机构信息

Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), 76128, Karlsruhe, Germany.

出版信息

Small. 2014 Oct 15;10(19):3863-8. doi: 10.1002/smll.201400813. Epub 2014 Jul 2.

Abstract

A novel surface functionalization technique is presented for large-scale selective molecule deposition onto whispering gallery mode microgoblet cavities. The parallel technique allows damage-free individual functionalization of the cavities, arranged on-chip in densely packaged arrays. As the stamp pad a glass slide is utilized, bearing phospholipids with different functional head groups. Coated microcavities are characterized and demonstrated as biosensors.

摘要

提出了一种新颖的表面功能化技术,用于大规模选择性分子沉积到声回廊模式微酒杯腔上。该平行技术允许对芯片上密集封装阵列中排列的腔进行无损伤的个体功能化。利用载玻片作为印模,其表面涂有具有不同官能团头的磷脂。对涂覆的微腔进行了特性分析,并将其用作生物传感器进行了演示。

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