Wiggans Matthew G, Shahtahmassebi Golnaz, Aroori Somaiah, Bowles Matthew J, Stell David A
Department of Hepatopancreatobiliary Surgery, Plymouth Hospitals National Health Service (NHS) Trust, Derriford Hospital, Plymouth, UK; Department of Medicine, Peninsula College of Medicine and Dentistry, Plymouth University, Plymouth, UK.
HPB (Oxford). 2015 Feb;17(2):150-8. doi: 10.1111/hpb.12290. Epub 2014 Jul 3.
The aim of this study was to compare the socioeconomic profile of patients undergoing liver resection for colorectal liver metastasis (CLM) in a regional hepatopancreatobiliary unit with that of the local population. A further aim was to determine if degree of deprivation is associated with tumour recurrence after resection.
A retrospective analysis of patients undergoing liver resection for CLM was performed. Geodemographic segmentation was used to divide the population into five categories of socioeconomic status (SES).
During a 7-year period, 303 patients underwent resection for CLM. The proportion of these patients in the two least deprived categories of SES was greater than that of the local population (50.2% versus 40.2%) and the proportion in the two most deprived categories was lower (18.3% versus 30.1%) (P < 0.001). There was no difference in recurrence rate (P = 0.867) or disease-free survival among categories of SES (P = 0.913). Multivariate analysis demonstrated no association between SES and tumour recurrence (P = 0.700).
Liver resection for CLM is performed more commonly among the least socioeconomically deprived population than among the most deprived. However, degree of deprivation was not associated with tumour recurrence after resection.
本研究旨在比较在一个地区性肝胆胰单位接受结直肠癌肝转移（CLM）肝切除术的患者与当地人群的社会经济概况。另一个目的是确定贫困程度是否与肝切除术后肿瘤复发相关。
对接受CLM肝切除术的患者进行回顾性分析。采用地理人口统计学细分方法将人群分为五类社会经济地位（SES）。
在7年期间，303例患者接受了CLM切除术。这些患者中处于SES最不贫困的两个类别的比例高于当地人群（50.2%对40.2%），而处于最贫困的两个类别的比例较低（18.3%对30.1%）（P<0.001）。SES各分类之间的复发率（P=0.867）或无病生存率无差异（P=0.913）。多变量分析显示SES与肿瘤复发之间无关联（P=0.700）。
CLM肝切除术在社会经济最不贫困人群中比在最贫困人群中更常见。然而，贫困程度与肝切除术后肿瘤复发无关。
