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[产青霉素的产黄青霉初始培养物和突变培养物的脂质]

[Lipids of initial and mutant cultures of Penicillium chrysogenum, producers of penicillin].

作者信息

Konova I V, Pan'kina O I, Lebed' E S, Bartoshevich Iu E

出版信息

Antibiot Khimioter. 1989 Jan;34(1):3-6.

PMID:2499283
Abstract

Comparative investigation of lipogenesis in 2 initial and 4 mutant strains of Penicillium chrysogenum showed that there were no noticeable differences in the composition of the lipid fatty acids in these strains. Certain shifts in the ratio of definite lipid fatty acids in the mutant strain deficient by synthesis of lysine and isoleucine (increased contents of oleic acid) were revealed. A marked influence of the physiological conditions on lipogenesis in the mutant with multiple deficiency by amino acids, vitamins and nucleotides was observed.

摘要

对2株产黄青霉原始菌株和4株突变菌株中脂肪生成的比较研究表明,这些菌株中脂质脂肪酸的组成没有明显差异。在赖氨酸和异亮氨酸合成缺陷的突变菌株中,特定脂质脂肪酸的比例出现了某些变化(油酸含量增加)。观察到生理条件对氨基酸、维生素和核苷酸多重缺陷的突变体中脂肪生成有显著影响。

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