Krefft K, Drogoszewska B, Kaminska J, Juniewicz M, Wołąkiewicz G, Jakacka I, Ciesielski B
Department of Physics and Biophysics, Medical University of Gdansk, Debinki 1, Gdansk 80-211, Poland
Department of Oral and Maxillofacial Surgery, University Clinical Center in Gdansk, Debinki 7, Gdansk 80-952, Poland.
Radiat Prot Dosimetry. 2014 Nov;162(1-2):38-42. doi: 10.1093/rpd/ncu214. Epub 2014 Jul 3.
In the present study, bone samples from three patients treated in radiotherapy facilities in Poland were used for the determination of doses absorbed during radiotherapy. The samples were obtained during surgical treatments of patients performed due to medical indications. For the purpose of retrospective dosimetry, sensitivity of the radiation-induced EPR signal was individually calibrated in the samples by re-irradiation of the samples with known doses. The doses reconstructed in bones extracted within 6 months after irradiation were consistent with those calculated by treatment planning systems. The dose reconstructed in the bone removed 6 y after radiotherapy was ∼14% lower than the calculated one.
在本研究中，取自波兰放疗机构接受治疗的三名患者的骨样本用于测定放疗期间吸收的剂量。这些样本是在因医疗指征对患者进行手术治疗期间获取的。为进行回顾性剂量测定，通过用已知剂量对样本进行再辐照，在样本中对辐射诱导的电子顺磁共振（EPR）信号的灵敏度进行了单独校准。在辐照后6个月内取出的骨骼中重建的剂量与治疗计划系统计算的剂量一致。放疗6年后取出的骨骼中重建的剂量比计算值低约14%。
