Rosén Robert, Lundström Linda, Venkataraman Abinaya Priya, Winter Simon, Unsbo Peter
Department of Applied Physics, Biomedical and X-ray Physics, Royal Institute of Technology, Stockholm, Sweden.
J Vis. 2014 Jul 3;14(8):3. doi: 10.1167/14.8.3.
Measuring the contrast sensitivity function (CSF) in the periphery of the eye is complicated. The lengthy measurement time precludes all but the most determined subjects. The aim of this study was to implement and evaluate a faster routine based on the quick CSF method (qCSF) but adapted to work in the periphery. Additionally, normative data is presented on neurally limited peripheral CSFs. A peripheral qCSF measurement using 100 trials can be performed in 3 min. The precision and accuracy were tested for three subjects under different conditions (number of trials, peripheral angles, and optical corrections). The precision for estimates of contrast sensitivity at individual spatial frequencies was 0.07 log units when three qCSF measurements of 100 trials each were averaged. Accuracy was estimated by comparing the qCSF results with a more traditional measure of CSF. Average accuracy was 0.08 log units with no systematic error. In the second part of the study, we collected three CSFs of 100 trials for six persons in the 20° nasal, temporal, inferior, and superior visual fields. The measurements were performed in an adaptive optics system running in a continuous closed loop. The Tukey HSD test showed significant differences (p < 0.05) between all fields except between the nasal and the temporal fields. Contrast sensitivity was higher in the horizontal fields, and the inferior field was better than the superior. This modified qCSF method decreases the measurement time significantly and allows otherwise unfeasible studies of the peripheral CSF.
测量眼外周的对比敏感度函数(CSF)很复杂。漫长的测量时间使得除了最有决心的受试者外,其他人都难以完成。本研究的目的是实施并评估一种基于快速CSF方法(qCSF)但适用于外周测量的更快流程。此外,还给出了神经限制外周CSF的规范数据。使用100次试验进行一次外周qCSF测量可在3分钟内完成。在不同条件(试验次数、外周角度和光学矫正)下对三名受试者的精度和准确性进行了测试。当对每次100次试验的三次qCSF测量结果求平均值时,单个空间频率下对比敏感度估计值的精度为0.07对数单位。通过将qCSF结果与更传统的CSF测量方法进行比较来估计准确性。平均准确性为0.08对数单位,无系统误差。在研究的第二部分,我们在20°鼻侧、颞侧、下方和上方视野中为六名受试者收集了三次各100次试验的CSF数据。测量在连续闭环运行的自适应光学系统中进行。Tukey HSD检验显示,除鼻侧和颞侧视野外,所有视野之间均存在显著差异(p < 0.05)。水平视野的对比敏感度更高,下方视野优于上方视野。这种改进的qCSF方法显著缩短了测量时间,并使得对外周CSF进行原本不可行的研究成为可能。