Prabhakar Amit, Mancuso Kenneth F, Owen Christopher Paul, Lissauer Jonathan, Merritt Christopher K, Urman Richard D, Kaye Alan David
Department of Anesthesiology, Louisiana State University School of Medicine, New Orleans, LA, USA.
Ochsner Clinic Foundation Anesthesiology Department, New Orleans, LA 70121, USA.
Best Pract Res Clin Anaesthesiol. 2014 Jun;28(2):105-15. doi: 10.1016/j.bpa.2014.04.005. Epub 2014 May 22.
Despite an appreciation for many unwanted physiological effects from inadequate pain postoperative relief, moderate to severe postoperative pain remains commonplace. Though treatment options have evolved in recent years, including improvement in medications, multimodal regimens, and regional anesthetic techniques, including ultrasound and continuous catheters, outcomes data indicate that many of these strategies are associated with varying degrees of morbidity and mortality. This review focuses on the importance of effective postoperative analgesia and both short- and long-term effects associated with inadequate management. A careful literature review of emphasizing treatment options and potential pathogenesis associated with these strategies is emphasized in this review.
尽管人们认识到术后疼痛缓解不足会带来许多不良生理影响,但中度至重度术后疼痛仍然很常见。近年来,治疗选择有所发展,包括药物改进、多模式方案以及区域麻醉技术(如超声和连续导管),但结果数据表明,这些策略中的许多都与不同程度的发病率和死亡率相关。本综述重点关注有效术后镇痛的重要性以及与管理不足相关的短期和长期影响。本综述强调对强调这些策略相关的治疗选择和潜在发病机制进行仔细的文献综述。