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长期使用阿片类药物患儿的围手术期管理

Perioperative management of the child on long-term opioids.

作者信息

Geary Tim, Negus Anna, Anderson Brian J, Zernikow Boris

机构信息

Department of Anaesthesia, Starship Children's Hospital, Auckland, New Zealand.

出版信息

Paediatr Anaesth. 2012 Mar;22(3):189-202. doi: 10.1111/j.1460-9592.2011.03737.x. Epub 2011 Nov 21.

Abstract

The strategies used to manage children exposed to long-term opioids are extrapolated from adult literature. Opioid consumption during the perioperative period is more than three times that observed in patients not taking chronic opioids. A sparing use of opioids in the perioperative period results in both poor pain management and withdrawal phenomena. The child's pre-existing opioid requirement should be maintained, and acute pain associated with operative procedures should be managed with additional analgesia. This usually comprises short-acting opioids, regional or local anesthesia, and adjuvant therapies. Long-acting opioids, transdermal opioid patches, and implantable pumps can be used to maintain the regular opioid requirement. Intravenous infusion, nurse controlled analgesia, patient-controlled analgesia, or oral formulations are invaluable for supplemental requirements postoperatively. Effective management requires more than simply increasing opioid dose during this time. Collaboration of the child, family, and all teams involved is necessary. While chronic pain or palliative care teams and other staff experienced with the care of children suffering chronic pain may have helpful input, many pediatric hospitals do not have chronic pain teams, and many patients receiving long-term opioids are not palliative. Acute pain services are appropriate to deal with those on long-term opioids in the perioperative setting and do so successfully in many centers. Staff caring for such children in the perioperative period should be aware of the challenges these children face and be educated before surgery about strategies for postoperative management and discharge planning.

摘要

用于管理长期使用阿片类药物的儿童的策略是从成人文献中推断出来的。围手术期的阿片类药物消耗量是未服用慢性阿片类药物患者的三倍多。围手术期过度节省使用阿片类药物会导致疼痛管理不佳和戒断现象。应维持儿童先前的阿片类药物需求量,与手术相关的急性疼痛应采用额外的镇痛措施进行处理。这通常包括短效阿片类药物、区域或局部麻醉以及辅助治疗。长效阿片类药物、透皮阿片类药物贴片和植入式泵可用于维持常规阿片类药物需求量。静脉输注、护士控制镇痛、患者自控镇痛或口服制剂对于术后补充需求非常重要。在此期间,有效的管理不仅仅是简单地增加阿片类药物剂量。儿童、家庭和所有相关团队的协作是必要的。虽然慢性疼痛或姑息治疗团队以及其他有照顾慢性疼痛儿童经验的工作人员可能会提供有用的建议,但许多儿科医院没有慢性疼痛团队,而且许多长期使用阿片类药物的患者并非姑息治疗患者。急性疼痛服务适用于处理围手术期长期使用阿片类药物的患者,并且在许多中心都能成功做到这一点。在围手术期照顾这些儿童的工作人员应意识到这些儿童面临的挑战,并在手术前接受关于术后管理和出院计划策略的教育。

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