Das Biplab, Chakravarthi Sudheer, Goyal Manoj Kumar, Modi Manish, Vyas Sameer, Lal Vivek, Prabhakar Sudesh, Ahuja Chirag
Department of Neurology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Department of Neurology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
J Neurol Sci. 2014 Aug 15;343(1-2):215-7. doi: 10.1016/j.jns.2014.05.062. Epub 2014 Jun 5.
Post-encephalitic parkinsonism (PEP) is believed to be caused by a viral illness which causes degeneration of the nerve cells in the substantia nigra, resulting in clinical parkinsonism. Although common during the period of the First World War, the diagnosis of PEP is rarely entertained today.
We report an adolescent boy of PEP, who was bedridden due to severe parkinsonism following the encephalitis attack. After relevant imaging and investigation, he was treated with levodopa which made him independent from a year long total dependent condition.
Encephalitis lethargica or PEP is one of the rare parkinsonian syndromes which may be amenable to treatment. Proper diagnosis and treatment may help the patient become ambulatory from the dreaded lethargic condition.
脑炎后帕金森综合征（PEP）被认为是由一种病毒性疾病引起的，该疾病会导致黑质神经细胞变性，从而引发临床帕金森综合征。虽然在第一次世界大战期间很常见，但如今PEP的诊断很少被考虑。
我们报告了一名患有PEP的青少年男孩，他在脑炎发作后因严重帕金森综合征而卧床不起。经过相关影像学检查和调查后，他接受了左旋多巴治疗，这使他从长达一年的完全依赖状态中恢复到能够自理。
昏睡性脑炎或PEP是罕见的帕金森综合征之一，可能可以进行治疗。正确的诊断和治疗可能有助于患者从可怕的昏睡状态恢复到能够行走。
