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[Role of c-myc protein in the early embryonic development of Xenopus].

作者信息

Méchali M, Evan G, Gusse M

机构信息

Institut Jacques-Monod, Paris.

出版信息

C R Acad Sci III. 1989;308(8):213-8.

PMID:2499407
Abstract

Microinjections of antibodies directed against the protein encoded by the c-myc protooncogene strongly inhibit or arrest the early cell cleavage stage of Xenopus laevis embryos. Injections in one blastomere of a two cell stage embryo inhibit the segmentation of this blastomere. The cleavage of the uninjected blastomere behaves normally. Injections of control rabbit immunoglobulins do not alter the embryonic development.

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