Larsen E
Department of Zoology, University of Toronto, Ontario, Canada.
Dev Genet. 1989;10(2):106-11. doi: 10.1002/dvg.1020100206.
Two modifiers of bithorax1 phenotypic expression are described. An X-chromosome region is associated with sexual dimorphism in bx1 penetrance. It is hypothesized that sexual dimorphism is in part due to a lack of dosage compensation of the modifier, in males. A third chromosome region that segregates with the pink peach allele is implicated in mediating temperature sensitivity. By appropriate combinations of modifiers, both sexual dimorphism and temperature sensitivity can be greatly reduced.
描述了双胸1表型表达的两个修饰因子。一个X染色体区域与bx1外显率的性别二态性相关。据推测，性别二态性部分是由于雄性中修饰因子缺乏剂量补偿所致。与粉红桃等位基因分离的第三个染色体区域与介导温度敏感性有关。通过修饰因子的适当组合，性别二态性和温度敏感性都可以大大降低。
