Department of Dermatology, University Hospitals Bristol, Bristol BS28HW, UK.
Occup Med (Lond). 2014 Oct;64(7):557-8. doi: 10.1093/occmed/kqu095. Epub 2014 Jul 2.
We report a case of an allergic skin reaction to ultraviolet-cured acrylates in a windscreen repair worker. The patient presented with a 6 month history of fingertip dryness, vesicles and desquamation. He had worked as a self-employed car windscreen repairer for 19 years. Previous management with vinyl glove protection and treatment with clobetasol propionate ointment had produced little improvement. He was patch tested to the British Society for Cutaneous Allergy standard and preservatives series and to the two acrylates used in his work environment, identified using safety data sheets, methyl methacrylate 2% pet and 2-hydroxyethylmethacrylate (2-HEMA) 2% pet. A positive reaction was seen at Day 4 to 2-HEMA, but all other patch tests were negative. An occupational allergic contact dermatitis to 2-HEMA was diagnosed. The patient was given avoidance advice and advised to use nitrile gloves. Although he was unable to give up his current work, he has continued his job using nitrile gloves with marked improvement.
我们报告了一例在汽车挡风玻璃修理工中发生的对紫外线固化丙烯酸酯的过敏皮肤反应。该患者表现为指尖干燥、水疱和脱屑，病史长达 6 个月。他作为一名个体汽车挡风玻璃修理工已经工作了 19 年。之前使用乙烯基手套防护并使用氯倍他索丙酸酯软膏治疗，但改善效果甚微。他进行了斑贴试验，包括英国皮肤过敏学会标准和防腐剂系列，以及使用安全数据表确定的他工作环境中使用的两种丙烯酸酯，即甲基丙烯酸甲酯 2% pet 和 2-羟乙基甲基丙烯酸酯（2-HEMA）2% pet。在第 4 天，他对 2-HEMA 呈阳性反应，但其他所有斑贴试验均为阴性。诊断为职业性过敏性接触性皮炎。患者被给予避免接触的建议，并建议使用丁腈手套。尽管他无法放弃目前的工作，但他继续使用丁腈手套工作，症状明显改善。
