Department of Otorhinolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, SUN Yat-sen University, Guangzhou 510630, China.
J Immunol Res. 2014;2014:963484. doi: 10.1155/2014/963484. Epub 2014 Jun 3.
The predominant distribution of γ δ T cells in the mucosal and epithelial tissues makes these unconventional lymphocytes the "guards" to contact external environment (like allergens) and to contribute to immune surveillance, as well as "vanguards" to participate in initiating mucosal inflammation. Therefore, γ δ T cells have been considered to bridge the innate and adaptive immunity. The role these cells play in allergy seems to be complicated and meaningful, so it makes sense to review the characteristics and role of γ δ T cells in allergic diseases.
γ δ T 细胞主要分布在黏膜和上皮组织中，使这些非传统淋巴细胞成为接触外部环境（如过敏原）和促进免疫监视的“卫士”，也是参与启动黏膜炎症的“先锋”。因此，γ δ T 细胞被认为是连接先天免疫和适应性免疫的桥梁。这些细胞在过敏中的作用似乎很复杂且有意义，因此，回顾 γ δ T 细胞在过敏性疾病中的特征和作用是有意义的。
