Chair of Nutritional Physiology, Department of Dietetics, Faculty of Human Nutrition and Consumer Sciences, Warsaw University of Life Sciences (SGGW), Nowoursynowska 159c, 02-776 Warsaw, Poland.
Food Funct. 2014 Sep;5(9):2096-105. doi: 10.1039/c4fo00108g.
Very little is known about the effects of red wine consumption on male reproductive functions. Here we report the effect of regular drinking of different types of red wine on hormonal reproductive parameters and total antioxidant status in young adult male rats. Dry red wine (D-RW) exerted higher antioxidant activity and was characterized by higher concentration of phenolic compounds compared to semi-dry (SD-RW), sweet (S-RW) and semi-sweet (SS-RW) wines. No differences in total antioxidant status of rat plasma after six weeks of drinking of the wines were detected. Increased plasma follicle-stimulating hormone levels in S-RW versus control and D-RW (5.26 vs. 3.06 and 3.21 ng mL(-1)) groups were found. The plasma testosterone concentration was lower in D-RW compared to control, SD-RW, S-RW and SS-RW groups (0.25 vs. 1.12, 1.09, 1.54 and 1.25 ng mL(-1)). Higher plasma 17β-estradiol level in S-RW versus SD-RW and SS-RW (10.94 vs. 7.18 and 6.72 pg mL(-1)) group was stated. The prolactin level was higher in plasma of S-RW versus D-RW and SS-RW (17.35 vs. 9.74 and 8.59 ng mL(-1)) rats. The effects of red wine drinking on the hormonal regulation of the male reproductive system depend on the type and the dose of red wine. Chemical compounds naturally occurring in red wines (i.e. phenolics) may modulate the effects of ethyl alcohol, but also directly affect the male reproduction.
关于红酒消费对男性生殖功能的影响知之甚少。在这里，我们报告了经常饮用不同类型的红酒对年轻成年雄性大鼠激素生殖参数和总抗氧化状态的影响。干红葡萄酒（D-RW）的抗氧化活性更高，其酚类化合物浓度也高于半干型（SD-RW）、甜型（S-RW）和半甜型（SS-RW）葡萄酒。六周饮用红酒后，大鼠血浆总抗氧化状态无差异。与对照组和 D-RW（5.26 对 3.06 和 3.21ng/ml）组相比，S-RW 组的血浆促卵泡激素水平升高。与对照组、SD-RW、S-RW 和 SS-RW 组相比，D-RW 组的血浆睾酮浓度较低（0.25 对 1.12、1.09、1.54 和 1.25ng/ml）。S-RW 组的血浆 17β-雌二醇水平高于 SD-RW 和 SS-RW 组（10.94 对 7.18 和 6.72pg/ml）。与 D-RW 和 SS-RW 组相比，S-RW 组大鼠血浆催乳素水平较高（17.35 对 9.74 和 8.59ng/ml）。红酒饮用对男性生殖系统激素调节的影响取决于红酒的类型和剂量。红酒中天然存在的化学物质（即酚类化合物）可能调节乙醇的作用，也可能直接影响男性生殖。
