Willey Joshua Z, Demmer Ryan T, Takayama Hiroo, Colombo Paolo C, Lazar Ronald M
Department of Neurology, Division of Stroke and Cerebrovascular Diseases, Columbia University, New York, New York.
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
J Heart Lung Transplant. 2014 Sep;33(9):878-87. doi: 10.1016/j.healun.2014.05.005. Epub 2014 Jun 2.
Cerebral infarction and hemorrhage are among the principal sources of morbidity and mortality associated with mechanical circulatory support. There has been particular concern with the recently reported increased rate of device thrombosis in continuous-flow left ventricular assist devices. The neurologic management of stroke among these patients has limited data to inform current clinical practices. In this investigation we review the available literature on stroke in patients with continuous-flow left ventricular assist devices, with a focus on treatment algorithms in the acute setting and for secondary stroke prevention.
脑梗死和脑出血是与机械循环支持相关的主要发病和死亡原因。最近有报道称，连续流左心室辅助装置中器械血栓形成的发生率有所增加，这引发了特别关注。这些患者中风的神经学管理方面的数据有限，难以指导当前的临床实践。在本研究中，我们回顾了关于连续流左心室辅助装置患者中风的现有文献，重点关注急性情况下和二级中风预防的治疗算法。
