Partsch C J, Kreller-Laugwitz G, Sippell W G
Abteilung Allgemeine Pädiatrie, Christian-Albrechts-Universität zu Kiel.
Monatsschr Kinderheilkd. 1989 Apr;137(4):235-8.
Precocious pseudopuberty in girls may be due to autonomous ovarian cysts. The spontaneous course in two girls aged 3.5 and 5.75 years is described. For differential diagnosis of the precocious pubertal development the following parameters were particularly helpful: growth curves, bone age determinations, repeated LHRH tests and serial sonographic examinations of ovaries and uterus. Since spontaneous regression of pubertal signs could be seen after a few weeks with complete resolution of the ovarian cysts and endocrinological parameters returning to normal after a few months, laparotomy and ovariectomy could be avoided in these two patients.
女孩性早熟假性青春期可能是由自主性卵巢囊肿引起的。本文描述了两名年龄分别为3.5岁和5.75岁女孩的自然病程。对于性早熟发育的鉴别诊断，以下参数特别有用：生长曲线、骨龄测定、重复的促性腺激素释放激素（LHRH）试验以及卵巢和子宫的系列超声检查。由于几周后可见青春期体征自然消退，卵巢囊肿完全消失，几个月后内分泌参数恢复正常，这两名患者避免了剖腹手术和卵巢切除术。
