40岁及以上与40岁以下乳腺癌患者的差异：乳房X光检查结果。

Differences between breast cancer patients younger and older than 40 years: mammographic findings.

作者信息

Zhao Yu-Mei, Wang Jian-Tao, Liu Jing, Wang Ju, Wang Hong-Li, Liu Pei-Fang

机构信息

Department of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China E-mail :

出版信息

Asian Pac J Cancer Prev. 2014;15(12):4929-32. doi: 10.7314/apjcp.2014.15.12.4929.

DOI:10.7314/apjcp.2014.15.12.4929

PMID:24998566

Abstract

OBJECTIVE

To compare the mammogarphic appearance between breast cancer patients aged <40 and ≥40 years.

METHODS

Needle localization and biopsy of suspicious mammographic lesions identified 1,959 breast carcinomas in a single institution from Jun 2012 to Apr 2013. According to the age, we divided patients into two groups: <40 and ≥40 years old, and analyzed mammographic appearance separately.

RESULTS

Young patients had 44.2% foci with calcification, but old patients only had 39.4% (P<0.001). In younger group, the ratios of cases according to mass density were 41.8% or higher, 58.2% equivalent and lower. In older group, the ratios were 55.5 % and 44.5%, respectively. There were statistical differences between high density and others (P<0.05). The ratios of cases according to mass margin were 13.9% circumscribed and microlobulated, 86.1% indistinct and spiculated in the younger group, as compared to 6.5% and 93.5%, respectively, in the older group (P<0.05).

CONCLUSIONS

Mammographic findings differ between young and old patients with breast cancer, for example regarding mass density, mass margin and microcalcification ratios.

摘要

目的

比较年龄小于40岁和大于等于40岁的乳腺癌患者的乳房X线表现。

方法

对2012年6月至2013年4月间在某单一机构通过针定位和活检确诊的1959例乳腺癌患者，根据年龄分为两组：小于40岁组和大于等于40岁组，并分别分析其乳房X线表现。

结果

年轻患者中44.2%的病灶有钙化，而老年患者仅有39.4%（P<0.001）。在较年轻组中，根据肿块密度划分的病例比例为密度较高者占41.8%或更高，密度相当及较低者占58.2%。在老年组中，相应比例分别为55.5%和44.5%。高密度与其他情况之间存在统计学差异（P<0.05）。根据肿块边缘划分的病例比例，在较年轻组中边界清晰和微叶状的占13.9%，边界不清和毛刺状的占86.1%，而在老年组中分别为6.5%和93.5%（P<0.05）。