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J Vis Exp. 2014 Jun 29(88):e4354. doi: 10.3791/4354.
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2
Inactivation of Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes on stored iceberg lettuce by aqueous chlorine dioxide treatment.用二氧化氯水溶液处理对储存的生菜上大肠杆菌O157:H7、鼠伤寒沙门氏菌和单核细胞增生李斯特菌的灭活作用。
J Food Sci. 2008 Nov;73(9):M418-22. doi: 10.1111/j.1750-3841.2008.00940.x.
3
Inactivation kinetics of inoculated Escherichia coli O157:H7 and Salmonella enterica on lettuce by chlorine dioxide gas.二氧化氯气体对接种在生菜上的大肠杆菌O157:H7和肠炎沙门氏菌的失活动力学
Food Microbiol. 2008 Apr;25(2):244-52. doi: 10.1016/j.fm.2007.10.015. Epub 2007 Nov 19.
4
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Food Microbiol. 2007 Oct-Dec;24(7-8):736-44. doi: 10.1016/j.fm.2007.03.006. Epub 2007 Mar 15.
5
Shelf-life extension of minimally processed carrots by gaseous chlorine dioxide.气态二氧化氯延长轻度加工胡萝卜的货架期
Int J Food Microbiol. 2007 May 10;116(2):221-7. doi: 10.1016/j.ijfoodmicro.2006.12.008. Epub 2007 Feb 15.
6
Mechanisms of killing of Bacillus subtilis spores by hypochlorite and chlorine dioxide.次氯酸盐和二氧化氯杀灭枯草芽孢杆菌孢子的机制
J Appl Microbiol. 2003;95(1):54-67. doi: 10.1046/j.1365-2672.2003.01960.x.
7
Thermal inactivation and injury of Bacillus stearothermophilus spores.嗜热脂肪芽孢杆菌孢子的热灭活与损伤
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便携式化学消毒器(PCS)、D-FENS和D-FEND ALL:用于军事领域的新型二氧化氯去污技术。

The Portable Chemical Sterilizer (PCS), D-FENS, and D-FEND ALL: novel chlorine dioxide decontamination technologies for the military.

作者信息

Doona Christopher J, Feeherry Florence E, Setlow Peter, Malkin Alexander J, Leighton Terrence J

机构信息

United States Army-Natick Soldier RD&E Center, Warfighter Directorate;

United States Army-Natick Soldier RD&E Center, Warfighter Directorate.

出版信息

J Vis Exp. 2014 Jun 29(88):e4354. doi: 10.3791/4354.

DOI:10.3791/4354
PMID:24998679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4208883/
Abstract

There is a stated Army need for a field-portable, non-steam sterilizer technology that can be used by Forward Surgical Teams, Dental Companies, Veterinary Service Support Detachments, Combat Support Hospitals, and Area Medical Laboratories to sterilize surgical instruments and to sterilize pathological specimens prior to disposal in operating rooms, emergency treatment areas, and intensive care units. The following ensemble of novel, 'clean and green' chlorine dioxide technologies are versatile and flexible to adapt to meet a number of critical military needs for decontamination(6,15). Specifically, the Portable Chemical Sterilizer (PCS) was invented to meet urgent battlefield needs and close critical capability gaps for energy-independence, lightweight portability, rapid mobility, and rugged durability in high intensity forward deployments(3). As a revolutionary technological breakthrough in surgical sterilization technology, the PCS is a Modern Field Autoclave that relies on on-site, point-of-use, at-will generation of chlorine dioxide instead of steam. Two (2) PCS units sterilize 4 surgical trays in 1 hr, which is the equivalent throughput of one large steam autoclave (nicknamed "Bertha" in deployments because of its cumbersome size, bulky dimensions, and weight). However, the PCS operates using 100% less electricity (0 vs. 9 kW) and 98% less water (10 vs. 640 oz.), significantly reduces weight by 95% (20 vs. 450 lbs, a 4-man lift) and cube by 96% (2.1 vs. 60.2 ft(3)), and virtually eliminates the difficult challenges in forward deployments of repairs and maintaining reliable operation, lifting and transporting, and electrical power required for steam autoclaves.

摘要

美国陆军表示需要一种可野战携带的非蒸汽消毒技术,供前沿外科手术队、牙科连、兽医勤务保障分队、战斗支援医院和地区医学实验室使用,以便在手术室、急诊治疗区和重症监护病房对手术器械进行消毒,并在处置病理标本前对其进行消毒。以下一系列新颖的“清洁环保”二氧化氯技术用途广泛且灵活,能够满足军事上一些关键的去污需求(6,15)。具体而言,便携式化学消毒器(PCS)的发明是为了满足紧急战场需求,并填补在高强度前沿部署中能源独立、轻便易携带、快速机动性和坚固耐用性方面的关键能力差距(3)。作为手术消毒技术的一项革命性技术突破,PCS是一种现代野战高压灭菌器,它依靠现场即时按需生成二氧化氯,而非蒸汽。两台PCS装置在1小时内可消毒4个手术托盘,这与一台大型蒸汽高压灭菌器的吞吐量相当(在部署中因其体积庞大、尺寸笨重和重量大而被昵称为“伯莎”)。然而,PCS运行时耗电量减少100%(0千瓦对9千瓦),用水量减少98%(10盎司对640盎司),重量显著减轻95%(20磅对450磅,需4人抬举),体积减小96%(2.1立方英尺对60.2立方英尺),并且几乎消除了蒸汽高压灭菌器在前沿部署中维修、保持可靠运行、搬运和电力供应方面的难题。