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基于日本公共卫生中心糖尿病研究中的一份自填问卷和一次健康检查的糖尿病患病率及糖化血红蛋白分布的描述性流行病学研究

Descriptive epidemiology of diabetes prevalence and HbA1c distributions based on a self-reported questionnaire and a health checkup in the JPHC diabetes study.

作者信息

Kabeya Yusuke, Kato Masayuki, Isogawa Akihiro, Takahashi Yoshihiko, Matsushita Yumi, Goto Atsushi, Iso Hiroyasu, Inoue Manami, Mizoue Tetsuya, Tsugane Shoichiro, Kadowaki Takashi, Noda Mitsuhiko

机构信息

Department of Diabetes Research, National Center for Global Health and Medicine.

出版信息

J Epidemiol. 2014;24(6):460-8. doi: 10.2188/jea.je20130196. Epub 2014 Jul 5.

Abstract

BACKGROUND

The present study examined the prevalence of diabetes in Japan during the late 1990s and early 2000s using the Japan Public Health Center-based Prospective Diabetes cohort. We also investigated the distributions of HbA1c values in noncompliant diabetic participants in the cohort.

METHODS

A total of 28 183 registered inhabitants aged 46-75 years from 10 public health center areas were included in the initial survey. The 5-year follow-up survey included 20 129 participants. The prevalence of diabetes was estimated using both a self-reported questionnaire and laboratory measurements. Among the participants who reported the presence of diabetes on the questionnaire (self-reported diabetes), the distributions of HbA1c values were described according to their treatment status.

RESULTS

The age-standardized prevalence of diabetes in 55- to 74-year-old adults was 8.2% at the initial survey and 10.6% at the 5-year follow-up. At the initial survey, among participants with self-reported diabetes, the mean HbA1c values in the participants who had never and who had previously received diabetes treatment were 7.01% (standard deviation [SD] 1.56%) and 6.56% (SD 1.46%), respectively. Approximately 15% of the participants who had self-reported diabetes but had never received diabetes treatment had an HbA1c ≥ 8.4%.

CONCLUSIONS

The prevalence of diabetes increased in the JPHC cohort between the late 1990s and early 2000s. A certain proportion of participants who were aware of their diabetes but were not currently receiving treatment had poor diabetic control. Efforts to promote continuous medical attendance for diabetes care may be necessary.

摘要

背景

本研究利用日本公共卫生中心前瞻性糖尿病队列,调查了20世纪90年代末和21世纪初日本糖尿病的患病率。我们还研究了该队列中未遵医嘱的糖尿病患者糖化血红蛋白(HbA1c)值的分布情况。

方法

初始调查纳入了来自10个公共卫生中心地区的28183名年龄在46 - 75岁的登记居民。5年随访调查包括20129名参与者。糖尿病患病率通过自我报告问卷和实验室检测进行评估。在问卷中报告患有糖尿病的参与者(自我报告糖尿病患者)中,根据其治疗状态描述HbA1c值的分布情况。

结果

在初始调查中,55至74岁成年人中糖尿病的年龄标准化患病率为8.2%,5年随访时为10.6%。在初始调查中,自我报告糖尿病的参与者中,从未接受过糖尿病治疗和之前接受过糖尿病治疗的参与者的平均HbA1c值分别为7.01%(标准差[SD]1.56%)和6.56%(SD 1.46%)。自我报告糖尿病但从未接受过糖尿病治疗的参与者中,约15%的人HbA1c≥8.4%。

结论

在20世纪90年代末至21世纪初期间,日本公共卫生中心队列中糖尿病患病率有所上升。一定比例知晓自己患有糖尿病但目前未接受治疗的参与者血糖控制不佳。可能需要努力促进糖尿病患者持续就医接受治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d73/4213220/95069c32358b/je-24-460-g001.jpg

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