• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一种用于乳腺癌近距离放射治疗的三维计算机辅助治疗计划系统。

A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment.

作者信息

Jiang Yuchong Rachel, Sykes Edward R

机构信息

Faculty of Applied Science and Technology, Sheridan College Institute of Technology and Advanced Learning, 1430 Trafalgar Road, Oakville, Ontario, Canada,

出版信息

Int J Comput Assist Radiol Surg. 2015 Apr;10(4):373-81. doi: 10.1007/s11548-014-1092-y. Epub 2014 Jul 8.

DOI:10.1007/s11548-014-1092-y
PMID:25001868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4379415/
Abstract

PURPOSE

Brachytherapy is an option for treatment of breast cancer in some cases. This modality requires patient-specific dosimetry based on CT simulator scans. A 3D computer-assisted breast brachytherapy treatment planning system called Vision was developed and tested.

METHODS

The brachytherapy treatment planning system used volume estimation and dose analysis with advanced 3D visualization. The patient treatment volume reconstruction was designed to ensure high-volume accuracy requirement of radioactive seed implantation procedure for this treatment. The system enables interactive placement of radioactive seeds embedded in original patient CT images with 3D display.

RESULTS

The system achieved 99.73% accuracy in volume estimation measured against the true volume and is statistically significantly more accurate than current existing commercial software at the p = 0.05 level.

CONCLUSION

A virtual 3D environment was developed to perform volume measurements, seed placements, and dose distribution planning and analysis based on 2D contours on patient CT images. This system was demonstrated to be feasible and accurate in a clinical setting.

摘要

目的

近距离放射疗法在某些情况下是治疗乳腺癌的一种选择。这种治疗方式需要基于CT模拟扫描进行患者特异性剂量测定。开发并测试了一种名为Vision的三维计算机辅助乳腺近距离放射治疗计划系统。

方法

近距离放射治疗计划系统采用体积估计和剂量分析，并具备先进的三维可视化功能。患者治疗体积重建旨在确保该治疗中放射性种子植入程序对高体积精度的要求。该系统能够在原始患者CT图像中交互式放置放射性种子并进行三维显示。

结果

该系统在体积估计方面相对于真实体积的准确率达到99.73%，在p = 0.05水平上，其准确性在统计学上显著高于现有的商业软件。

结论

开发了一个虚拟三维环境，用于基于患者CT图像上的二维轮廓进行体积测量、种子放置以及剂量分布规划和分析。该系统在临床环境中被证明是可行且准确的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/12fbf29f383e/11548_2014_1092_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/b8d1807000bd/11548_2014_1092_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/c37463eddaa9/11548_2014_1092_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/65a2e3a0c4b6/11548_2014_1092_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/1f2ee27f3632/11548_2014_1092_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/15c5561bdf89/11548_2014_1092_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/8fbca9650958/11548_2014_1092_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/4d992ff5414f/11548_2014_1092_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/5b2623858e58/11548_2014_1092_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/e2da856f4b7b/11548_2014_1092_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/12fbf29f383e/11548_2014_1092_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/b8d1807000bd/11548_2014_1092_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/c37463eddaa9/11548_2014_1092_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/65a2e3a0c4b6/11548_2014_1092_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/1f2ee27f3632/11548_2014_1092_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/15c5561bdf89/11548_2014_1092_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/8fbca9650958/11548_2014_1092_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/4d992ff5414f/11548_2014_1092_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/5b2623858e58/11548_2014_1092_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/e2da856f4b7b/11548_2014_1092_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964b/4379415/12fbf29f383e/11548_2014_1092_Fig10_HTML.jpg

相似文献

1
A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment.一种用于乳腺癌近距离放射治疗的三维计算机辅助治疗计划系统。
Int J Comput Assist Radiol Surg. 2015 Apr;10(4):373-81. doi: 10.1007/s11548-014-1092-y. Epub 2014 Jul 8.
2
Validation of a novel robot-assisted 3DUS system for real-time planning and guidance of breast interstitial HDR brachytherapy.一种新型机器人辅助三维超声系统用于乳腺组织间高剂量率近距离放疗实时计划与引导的验证
Med Phys. 2015 Dec;42(12):6830-9. doi: 10.1118/1.4934832.
3
Incorporating three-dimensional ultrasound into permanent breast seed implant brachytherapy treatment planning.将三维超声纳入永久性乳腺籽源植入近距离放射治疗计划。
Brachytherapy. 2017 Jan-Feb;16(1):167-173. doi: 10.1016/j.brachy.2016.09.007. Epub 2016 Oct 19.
4
Computed tomography for excision cavity localization and 3D-treatment planning in partial breast irradiation with high-dose-rate interstitial brachytherapy.计算机断层扫描在高剂量率组织间近距离放射治疗部分乳腺照射中用于切除腔定位和三维治疗计划。
Radiother Oncol. 2009 Jan;90(1):43-7. doi: 10.1016/j.radonc.2007.10.029. Epub 2007 Nov 26.
5
Evaluation of HDR interstitial breast implants planned by conventional and optimized CT-based dosimetry systems with respect to dose homogeneity and conformality.基于传统和优化的CT剂量测定系统对高剂量率间质乳腺植入物的剂量均匀性和适形性进行评估。
Strahlenther Onkol. 2005 Feb;181(2):89-96. doi: 10.1007/s00066-005-1350-6.
6
Implementation of 3D-virtual brachytherapy in the management of breast cancer: a description of a new method of interstitial brachytherapy.三维虚拟近距离放射治疗在乳腺癌管理中的应用：一种间质近距离放射治疗新方法的描述
Int J Radiat Oncol Biol Phys. 1998 Feb 1;40(3):629-35. doi: 10.1016/s0360-3016(97)00499-9.
7
CT-image-based conformal brachytherapy of breast cancer. The significance of semi-3-D and 3-D treatment planning.基于CT图像的乳腺癌适形近距离放射治疗。半三维和三维治疗计划的意义。
Strahlenther Onkol. 2000 Mar;176(3):118-24. doi: 10.1007/pl00002336.
8
Dose-volume analysis for quality assurance of interstitial brachytherapy for breast cancer.用于乳腺癌间质近距离放疗质量保证的剂量体积分析
Int J Radiat Oncol Biol Phys. 1999 Oct 1;45(3):803-10. doi: 10.1016/s0360-3016(99)00174-1.
9
Improving the dosimetric coverage of interstitial high-dose-rate breast implants.提高间质高剂量率乳腺植入物的剂量覆盖范围。
Int J Radiat Oncol Biol Phys. 2000 Jan 1;46(1):35-43. doi: 10.1016/s0360-3016(99)00361-2.
10
3D CT-based high-dose-rate breast brachytherapy implants: treatment planning and quality assurance.基于3D CT的高剂量率乳腺近距离放射治疗植入：治疗计划与质量保证。
Int J Radiat Oncol Biol Phys. 2004 Jul 15;59(4):1224-8. doi: 10.1016/j.ijrobp.2004.03.030.

引用本文的文献

1
Automatic seed picking for brachytherapy postimplant validation with 3D CT images.基于 3D CT 图像的近距离治疗后验证的自动种子提取。
Int J Comput Assist Radiol Surg. 2017 Nov;12(11):1985-1993. doi: 10.1007/s11548-017-1632-3. Epub 2017 Jun 22.

本文引用的文献

1
Breast brachytherapy versus whole-breast irradiation: reported differences may be statistically significant but clinically trivial.
Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(2):266-8. doi: 10.1016/j.ijrobp.2013.12.002.
2
Comparative effectiveness research in radiation oncology: stereotactic radiosurgery, hypofractionation, and brachytherapy.放射肿瘤学中的比较疗效研究：立体定向放射外科、低分割和近距离放射治疗。
Semin Radiat Oncol. 2014 Jan;24(1):35-42. doi: 10.1016/j.semradonc.2013.08.004.
3
Benefit of adjuvant brachytherapy versus external beam radiation for early breast cancer: impact of patient stratification on breast preservation.辅助近距离放疗与外照射放疗治疗早期乳腺癌的获益：患者分层对保乳的影响。
Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(2):274-84. doi: 10.1016/j.ijrobp.2013.07.011. Epub 2013 Nov 21.
4
Extended (5-year) outcomes of accelerated partial breast irradiation using MammoSite balloon brachytherapy: patterns of failure, patient selection, and dosimetric correlates for late toxicity.应用 MammoSite 球囊近距离放疗行加速部分乳腺照射的 5 年扩展结果：失败模式、患者选择和晚期毒性的剂量学相关性。
Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(2):285-91. doi: 10.1016/j.ijrobp.2013.05.039. Epub 2013 Nov 21.
5
Optimization-based dosimetry planning for brachytherapy.基于优化的近距离放射治疗剂量测定计划
Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:5569-72. doi: 10.1109/IEMBS.2011.6091347.
6
Partial breast irradiation: a review of techniques and indications.部分乳房照射：技术与适应证的综述。
Br J Radiol. 2010 May;83(989):369-78. doi: 10.1259/bjr/11505970. Epub 2010 Mar 11.
7
Virtual planning of multicatheter brachytherapy implants for accelerated partial breast irradiation.用于加速部分乳腺照射的多导管近距离放射治疗植入的虚拟规划。
Conf Proc IEEE Eng Med Biol Soc. 2004;2004:3124-7. doi: 10.1109/IEMBS.2004.1403882.
8
First report of a permanent breast 103Pd seed implant as adjuvant radiation treatment for early-stage breast cancer.首例永久性乳腺103Pd粒子植入作为早期乳腺癌辅助放疗的报道。
Int J Radiat Oncol Biol Phys. 2006 Jan 1;64(1):176-81. doi: 10.1016/j.ijrobp.2005.06.031. Epub 2005 Sep 22.
9
MRI definition of target volumes using fuzzy logic method for three-dimensional conformal radiation therapy.
Int J Radiat Oncol Biol Phys. 2003 Jan 1;55(1):225-33. doi: 10.1016/s0360-3016(02)03829-4.
10
Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.一项比较全乳切除术、乳房肿瘤切除术以及乳房肿瘤切除术加放疗治疗浸润性乳腺癌的随机试验的20年随访。
N Engl J Med. 2002 Oct 17;347(16):1233-41. doi: 10.1056/NEJMoa022152.