Martinez-Gonzalez M A, Sayon-Orea C, Ruiz-Canela M, de la Fuente C, Gea A, Bes-Rastrollo M
Dept. Preventive Medicine and Public Health, University of Navarra, Spain; CIBERobn, Instituto de Salud Carlos III (ISCIII), Spain.
Dept. Preventive Medicine and Public Health, University of Navarra, Spain.
Nutr Metab Cardiovasc Dis. 2014 Nov;24(11):1189-96. doi: 10.1016/j.numecd.2014.05.015. Epub 2014 Jun 15.
Epidemiological studies on the association between yogurt consumption and the risk of overweight/obesity are scarce. We prospectively examined the association of yogurt consumption with overweight/obesity and average annual weight gain.
Prospective cohort study of 8516 men and women (mean age 37.1, SD: 10.8 y). Participants were followed-up every two years. Participants were classified in 5 categories of yogurt consumption at baseline: 0-2, >2-<5, 5-<7, 7 and ≥ 7 servings/week. Outcomes were: 1) average yearly weight change during follow-up; and 2) incidence of overweight/obesity. Linear regression models and Cox models were used to adjust for potential confounders. After a median follow-up of 6.6 years, 1860 incident cases of overweight/obesity were identified. A high (>7 servings/week) consumption of total and whole-fat yogurt was associated with lower incidence of overweight/obesity [multivariable adjusted hazard ratios = 0.80 (95% CI: 0.68-0.94); and 0.62 (0.47-0.82) respectively] in comparison with low consumption (0-2 servings/week). This inverse association was stronger among participants with higher fruit consumption.
In this Mediterranean cohort, yogurt consumption was inversely associated with the incidence of overweight/obesity, especially among participants with higher fruit consumption.
关于食用酸奶与超重/肥胖风险之间关联的流行病学研究较少。我们前瞻性地研究了食用酸奶与超重/肥胖及平均年体重增加之间的关联。
对8516名男性和女性(平均年龄37.1岁,标准差:10.8岁)进行前瞻性队列研究。参与者每两年随访一次。在基线时,参与者被分为5类酸奶食用量:每周0 - 2份、>2 - <5份、5 - <7份、7份及≥7份。观察结果为:1)随访期间的平均年体重变化;2)超重/肥胖的发生率。使用线性回归模型和Cox模型对潜在混杂因素进行调整。在中位随访6.6年后,确定了1860例超重/肥胖的新发病例。与低食用量(每周0 - 2份)相比,高食用量(每周>7份)的全脂酸奶和低脂酸奶与超重/肥胖的发生率较低相关[多变量调整风险比分别为0.80(95%置信区间:0.68 - 0.94)和0.62(0.47 - 0.82)]。这种负相关在水果食用量较高的参与者中更强。
在这个地中海队列中,食用酸奶与超重/肥胖的发生率呈负相关,尤其是在水果食用量较高的参与者中。