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学龄前儿童哮喘:诊断挑战综述

Asthma in preschool children: a review of the diagnostic challenges.

作者信息

Cave Andrew J, Atkinson Lana L

机构信息

From the Department of Family Medicine, University of Alberta, Edmonton, Alberta, Canada.

出版信息

J Am Board Fam Med. 2014 Jul-Aug;27(4):538-48. doi: 10.3122/jabfm.2014.04.130276.

Abstract

Family physicians face many challenges when diagnosing asthma in preschool children. These diagnostic challenges are compounded by variations in the natural history of early stage asthma, which are not fully understood, since early childhood wheezing and asthma are heterogeneous disorders with many phenotypic and variable expressions. Since no standard definition for the type, severity, or frequency of symptoms exist for this age group, clear evidence-based recommendations are lacking. Without adequate guidance, family physicians are left to make diagnostic and treatment decisions, which can lead to undertreatment of asthmatics and overtreatment of transient wheezers. New guidelines that specifically address the challenges of diagnosing asthma in this particular age group (Global Initiative for Asthma, British Thoracic Society/Scottish Intercollegiate Guidelines Network) have recently been published, and researchers are actively seeking new methods and techniques through epidemiological studies to assist primary care clinicians in the diagnostic process. This review has wide application in primary care. By recognizing the diagnostic challenges and understanding the related best practices, family physicians will be better placed to treat, manage, and control asthma symptoms, resulting in lower morbidity rates and reduced health system costs, as well as enhancing the overall quality of life and well-being of the children affected.

摘要

在诊断学龄前儿童哮喘时,家庭医生面临诸多挑战。早期哮喘自然病史的差异使这些诊断挑战更加复杂,因为幼儿喘息和哮喘是具有多种表型和可变表现的异质性疾病,而我们对此尚未完全了解。由于该年龄组症状的类型、严重程度或频率没有标准定义,因此缺乏明确的循证建议。在没有充分指导的情况下,家庭医生只能自行做出诊断和治疗决策,这可能导致哮喘患者治疗不足以及对短暂喘息者过度治疗。最近发布了专门针对这一特定年龄组哮喘诊断挑战的新指南(全球哮喘防治创议、英国胸科学会/苏格兰校际指南网络),研究人员正在通过流行病学研究积极寻找新的方法和技术,以协助初级保健临床医生进行诊断过程。本综述在初级保健中有广泛应用。通过认识到诊断挑战并了解相关的最佳实践,家庭医生将更有能力治疗、管理和控制哮喘症状,从而降低发病率、减少卫生系统成本,同时提高受影响儿童的整体生活质量和幸福感。

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