Mishra Sudhansu Sekhar, Behera Sanjay Kumar, Dhir Manmath Kumar, Senapati Satya Bhusan
Department of Neurosurgery, Shrirama Chandra Bhanj Medical College and Hospital, Cuttack, Odisha, India.
J Neurosci Rural Pract. 2014 Jul;5(3):295-7. doi: 10.4103/0976-3147.133615.
Cerebellar glioblastoma multiforme (GBM) is a rare tumor that accounts for only 1% of all cases of GBM and its giant cell variant is even much rarely encountered in adults. A case of cerebellar giant cell GBM managed at our institution reporting its clinical presentation, radiological and histological findings, and treatment instituted is described. In conjunction, a literature review, including particular issues, clinical data, advances in imaging studies, pathological characteristics, treatment options, and the behavior of such malignant tumor is presented. It is very important for the neurosurgeon to make the differential diagnosis between the cerebellar GBM, and other diseases such as metastasis, anaplastic astrocytomas, and cerebellar infarct because their treatment modalities, prognosis, and outcome are different.
小脑多形性胶质母细胞瘤（GBM）是一种罕见肿瘤，仅占所有GBM病例的1%，其巨细胞变体在成人中更为罕见。本文描述了我院收治的一例小脑巨细胞GBM病例，报告了其临床表现、影像学和组织学检查结果以及所采取的治疗措施。同时，还进行了文献综述，包括特殊问题、临床数据、影像学研究进展、病理特征、治疗选择以及这种恶性肿瘤的行为。对于神经外科医生来说，鉴别小脑GBM与其他疾病（如转移瘤、间变性星形细胞瘤和小脑梗死）非常重要，因为它们的治疗方式、预后和结局各不相同。
