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Bone histomorphometry of transiliac paired bone biopsies after 6 or 12 months of treatment with oral strontium ranelate in 387 osteoporotic women: randomized comparison to alendronate.387名骨质疏松女性接受口服雷奈酸锶治疗6个月或12个月后经髂骨成对骨活检的骨组织形态计量学：与阿仑膦酸钠的随机对照比较
J Bone Miner Res. 2014 Mar;29(3):618-28. doi: 10.1002/jbmr.2074.
2
Clinical and surgical approach of severe bone fragility fracture: clinical case of 4 fragility fracture in patient with heavy osteoporosis.重度骨质疏松性骨折的临床与手术治疗方法：1例重度骨质疏松患者发生4处脆性骨折的临床病例
Clin Cases Miner Bone Metab. 2013 Jan;10(1):52-5. doi: 10.11138/ccmbm/2013.10.1.052.
3
Efficacy and safety of strontium ranelate in the treatment of osteoporosis in men.雷奈酸锶治疗男性骨质疏松症的疗效和安全性。
J Clin Endocrinol Metab. 2013 Feb;98(2):592-601. doi: 10.1210/jc.2012-3048. Epub 2013 Jan 22.
4
Healing of subtrochanteric atypical fractures after strontium ranelate treatment.雷奈酸锶治疗后股骨转子下非典型骨折的愈合情况。
Clin Cases Miner Bone Metab. 2012 Sep;9(3):166-9. Epub 2012 Dec 20.
5
Effects of strontium on the quality of bone apatite crystals: a paired biopsy study in postmenopausal osteoporotic women.锶对骨磷灰石晶体质量的影响：绝经后骨质疏松妇女配对活检研究。
Osteoporos Int. 2013 Mar;24(3):1079-87. doi: 10.1007/s00198-012-2181-9. Epub 2012 Oct 30.
6
Teriparatide therapy for bisphosphonate-associated osteonecrosis of the jaw in an elderly Japanese woman with severe osteoporosis.特立帕肽治疗老年日本严重骨质疏松症伴双膦酸盐相关性颌骨骨坏死 1 例
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7
Chronic mandibular osteomyelitis with suspected underlying synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome: a case report.慢性下颌骨骨髓炎伴疑似潜在滑膜炎、痤疮、脓疱病、骨质增生和骨炎（SAPHO）综合征：一例报告。
J Inflamm Res. 2012;5:29-35. doi: 10.2147/JIR.S29981. Epub 2012 Feb 27.
8
Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. Results of a 2-year study.雷奈酸锶和阿仑膦酸钠对骨质疏松症妇女骨微观结构的影响。一项为期 2 年的研究结果。
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9
A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX(®).一项锶雷奈酸酯对绝经后骨质疏松症患者椎体和非椎体骨折风险影响的荟萃分析及与 FRAX(®)的交互作用
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10
Possible benefits of strontium ranelate in complicated long bone fractures.锶雷尼酸酯在复杂长骨骨折中的可能益处。
Rheumatol Int. 2012 Feb;32(2):439-43. doi: 10.1007/s00296-010-1687-8. Epub 2010 Dec 1.

雷奈酸锶改善了一名慢性骨髓炎男性患者颌骨溶骨性病变的延迟愈合。病例报告。

Strontium ranelate improves delayed healing of osteolytic lesions of the jaw in a man with chronic osteomyelitis. Case report.

作者信息

Stathopoulos Konstantinos D, Giannitsioti Efthymia, Fragkou Archondoula N, Zoubos Aristides B, Papaggelopoulos Panagiotis J, Skarantavos Grigoris

机构信息

Bone Metabolic Unit, 1 Department of Orthopedics, University of Athens, School of Medicine, "Attikon" University General Hospital, Athens, Greece.

4 Department of Internal Medicine, "Attikon" University General Hospital, Athens, Greece.

出版信息

Clin Cases Miner Bone Metab. 2014 Jan;11(1):77-81.

PMID:25002884
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4064446/
Abstract

We report the case of a man with osteolytic lesions of the right mandible due to chronic osteomyelitis, with delayed healing after six months of antibiotic therapy. The patient received off-label therapy with strontium ranelate, with significant radiological improvement of his condition after 3 months.

摘要

我们报告了一例因慢性骨髓炎导致右下颌骨溶骨性病变的男性病例，在接受抗生素治疗六个月后愈合延迟。该患者接受了雷奈酸锶的超适应症治疗，3个月后其病情在影像学上有显著改善。