功能失调患者体内的重金属与疼痛
Heavy metals and pain in the dysfunctional patient.
作者信息
Di Paolo Carlo, Serritella Emanuela, Panti Fabrizio, Falisi Giovanni, Manna Fedele
机构信息
Department of Oral and Maxillo-facial Sciences Sapienza University of Rome, Italy.
出版信息
Ann Stomatol (Roma). 2014 Jun 18;5(2):41-51. eCollection 2014 Apr.
AIMS
The aim of this research is to verify the quality and quantity of heavy metals (HM) of dental origin in TMD patients.
METHODS
A population of 100 subject was studied and divided in two homogeneous groups: Study Group (SG) and Control Group (CG). Organism heavy metals were tested by a spot sampling method in which the first urine of the day, through Inductively Coupled Plasma-Mass Spectrometry (ICP-MS), were analyzed. The results obtained were compared with reference values (RV) of Italian people. Descriptive statistical analysis and student's t-test has been applied (statistical significance for p > 0.05).
RESULTS
The SG presented the absolute highest levels of HM compared to the CG (p=0.787). As regards the relation between pain and HM, the subjects that refer "severe/very severe" values of pain present the highest levels of HM in urines.
CONCLUSIONS
The obtained results seem to highlight a possible direct proportionality between the level of pain the increase of the concentration of heavy metals in all the examined groups and subgroups.
目的
本研究旨在验证颞下颌关节紊乱病（TMD）患者牙齿来源的重金属（HM）的质量和数量。
方法
对100名受试者进行研究，并将其分为两个同质组：研究组（SG）和对照组（CG）。通过斑点采样法检测生物体中的重金属，即通过电感耦合等离子体质谱法（ICP-MS）分析当天的首次尿液。将获得的结果与意大利人的参考值（RV）进行比较。应用了描述性统计分析和学生t检验（p>0.05具有统计学意义）。
结果
与对照组相比，研究组呈现出绝对最高水平的重金属（p = 0.787）。关于疼痛与重金属的关系，报告“严重/非常严重”疼痛值的受试者尿液中重金属水平最高。
结论
获得的结果似乎突出了在所有检查的组和亚组中，疼痛程度与重金属浓度增加之间可能存在的直接比例关系。
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