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2014年结核病峰会:结核病的预防、诊断与治疗——欧洲科学协会会议报告

TB Summit 2014: prevention, diagnosis, and treatment of tuberculosis-a meeting report of a Euroscicon conference.

作者信息

Maitra Arundhati, Bhakta Sanjib

机构信息

Mycobacteria Research Laboratory; Institute of Structural and Molecular Biology; University of London; London, UK.

出版信息

Virulence. 2014 Jul 1;5(5):638-44. doi: 10.4161/viru.29803. Epub 2014 Jul 8.

Abstract

World TB Day commemorates Dr Robert Koch's first announcement on March 24, 1882, that the bacterium Mycobacterium tuberculosis is the causative agent of tuberculosis. Currently, the event comprises of several conferences, meetings and activities held all over the world with the singular intention of raising public awareness about the global health emergency. In spite of having discovered the etiological agent of tuberculosis more than a century ago, a sizeable population still contract the disease every year and fall prey to it. In 2012, an estimated 8.6 million people developed the disease with 1.3 million succumbing to it. The number of TB deaths in children is unacceptably large, given that most are preventable. However, the challenge appears to be shifting toward attempts to control the rise and spread of the drug resistant variants of the microbe. To achieve this, a concerted effort from academia, clinical practice, and industry has been put forth. The TB Summit 2014 attempted to raise awareness as well as bring together experts involved in different aspects of tuberculosis research to help establish a more collective approach to battle this age-old disease.

摘要

世界防治结核病日是为纪念罗伯特·科赫博士于1882年3月24日首次宣布结核分枝杆菌是结核病的病原体。目前,这一活动包括在世界各地举行的若干会议和活动,其唯一目的是提高公众对这一全球卫生紧急情况的认识。尽管在一个多世纪前就已发现结核病的病原体,但每年仍有相当数量的人感染这种疾病并深受其害。2012年,估计有860万人患上该病,其中130万人死亡。儿童结核病死亡人数多得令人无法接受,因为大多数死亡是可以预防的。然而,挑战似乎正转向试图控制这种微生物耐药变种的增加和传播。为实现这一目标,学术界、临床实践和业界已共同努力。2014年结核病峰会试图提高认识,并召集参与结核病研究不同方面的专家,以帮助建立一种更具集体性的方法来对抗这种古老的疾病。

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Bedaquiline for the treatment of resistant tuberculosis: promises and pitfalls.用于治疗耐药结核病的贝达喹啉:前景与陷阱
Tuberculosis (Edinb). 2014 Jul;94(4):357-62. doi: 10.1016/j.tube.2014.04.001. Epub 2014 Apr 18.
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Improving the health of the tuberculosis drug pipeline.改善结核病药物研发进程中的药物状况。
Lancet Infect Dis. 2014 Feb;14(2):102-3. doi: 10.1016/s1473-3099(14)70006-4.
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Tuberculosis rates unacceptably high in UK cities.英国城市的结核病发病率高得令人无法接受。
Lancet Infect Dis. 2013 Oct;13(10):836-7. doi: 10.1016/s1473-3099(13)70276-7.

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