Klose Thomas, Rossmann Michael G
Biol Chem. 2014 Jul;395(7-8):711-9. doi: 10.1515/hsz-2014-0145.
Nucleocytoplasmic large dsDNA viruses (NCLDVs) encompass an ever-increasing group of large eukaryotic viruses, infecting a wide variety of organisms. The set of core genes shared by all these viruses includes a major capsid protein with a double jelly-roll fold forming an icosahedral capsid, which surrounds a double layer membrane that contains the viral genome. Furthermore, some of these viruses, such as the members of the Mimiviridae and Phycodnaviridae have a unique vertex that is used during infection to transport DNA into the host.
核质大双链DNA病毒(NCLDVs)包含越来越多的大型真核病毒,可感染多种生物。所有这些病毒共有的一组核心基因包括一种主要衣壳蛋白,其具有形成二十面体衣壳的双果冻卷折叠结构,该衣壳围绕着包含病毒基因组的双层膜。此外,其中一些病毒,如 Mimiviridae 和 Phycodnaviridae 的成员,具有一个独特的顶点,在感染过程中用于将DNA转运到宿主细胞中。