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肝细胞癌与肝内胆管癌在肝脏两叶同步发生。

Synchronous occurrence of hepatocellular carcinoma and intrahepatic cholangiocarcinoma in both lobes of the liver.

作者信息

Topaloğlu Serdar, Sağlam Kutay, Çalık Adnan, Cobanoğlu Ümit, Öztürk Mehmet Halil

机构信息

Department of Surgery, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey.

出版信息

Turk J Gastroenterol. 2014 Apr;25(2):209-11. doi: 10.5152/tjg.2014.6188.

DOI:10.5152/tjg.2014.6188
PMID:25003684
Abstract

Occurrence of synchronous double primary liver cancer is a very rare condition. A 48-year-old man underwent lateral sectorectomy and tumor resection from segment (S) 7 and S5 for 3 separate liver tumors. Pathological examination revealed intrahepatic cholangiocarcinoma (ICC) in the lateral sector and hepatocellular carcinoma (HCC) in S7 and S5. This report presents the second case in the literature describing the resection of synchronous double cancers of HCC and ICC localized in both lobes of the liver. We also reviewed the clinical and pathological aspects of this coincidental situation.

摘要

同步性双原发性肝癌的发生是一种非常罕见的情况。一名48岁男性因3个独立的肝脏肿瘤接受了肝外侧叶切除术以及来自第7和第5肝段的肿瘤切除术。病理检查显示肝外侧叶为肝内胆管癌(ICC),第7和第5肝段为肝细胞癌(HCC)。本报告介绍了文献中第二例描述肝两叶均存在的同步性肝细胞癌和肝内胆管癌双癌切除的病例。我们还回顾了这种巧合情况的临床和病理方面。

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Synchronous double primary hepatocellular carcinoma and intrahepatic cholangiocarcinoma in a single patient with chronic hepatitis B: two case reports and literature review.一名慢性乙型肝炎患者同时发生原发性肝细胞癌和肝内胆管癌:两例报告及文献复习
Front Oncol. 2025 Jun 16;15:1507454. doi: 10.3389/fonc.2025.1507454. eCollection 2025.
2
Multidisciplinary Approach to Perihilar and Intrahepatic Cholangiocarcinoma: A Single-Center Experience.肝门部及肝内胆管癌的多学科治疗方法:单中心经验
Turk J Gastroenterol. 2024 Nov 11;36(1):34-44. doi: 10.5152/tjg.2024.24301.