Vale Beatriz, Brito Sara, Paulos Lígia, Moleiro Pascoal
Hospital Pediátrico Carmona de Mota, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.
Centro Hospitalar de Leiria, Leiria, Portugal.
Einstein (Sao Paulo). 2014 Apr;12(2):175-80. doi: 10.1590/s1679-45082014ao2942.
To analyse the progression of body mass index in eating disorders and to determine the percentile for establishment and resolution of the disease.
A retrospective descriptive cross-sectional study. Review of clinical files of adolescents with eating disorders.
Of the 62 female adolescents studied with eating disorders, 51 presented with eating disorder not otherwise specified, 10 anorexia nervosa, and 1 bulimia nervosa. Twenty-one of these adolescents had menstrual disorders; in that, 14 secondary amenorrhea and 7 menstrual irregularities (6 eating disorder not otherwise specified, and 1 bulimia nervosa). In average, in anorectic adolescents, the initial body mass index was in 75th percentile; secondary amenorrhea was established 1 month after onset of the disease; minimum weight was 76.6% of ideal body mass index (at 4th percentile) at 10.2 months of disease; and resolution of amenorrhea occurred at 24 months, with average weight recovery of 93.4% of the ideal. In eating disorder not otherwise specified with menstrual disorder (n=10), the mean initial body mass index was at 85th percentile; minimal weight was in average 97.7% of the ideal value (minimum body mass index was in 52nd percentile) at 14.9 months of disease; body mass index stabilization occurred at 1.6 year of disease; and mean body mass index was in 73rd percentile. Considering eating disorder not otherwise specified with secondary amenorrhea (n=4); secondary amenorrhea occurred at 4 months, with resolution at 12 months of disease (mean 65th percentile body mass index).
One-third of the eating disorder group had menstrual disorder - two-thirds presented with amenorrhea. This study indicated that for the resolution of their menstrual disturbance the body mass index percentiles to be achieved by female adolescents with eating disorders was 25-50 in anorexia nervosa, and 50-75, in eating disorder not otherwise specified.
分析饮食失调患者体重指数的变化情况，并确定疾病发生和缓解时的百分位数。
一项回顾性描述性横断面研究。回顾饮食失调青少年的临床档案。
在研究的62名患有饮食失调的女性青少年中，51例为未特定的饮食失调，10例为神经性厌食症，1例为神经性贪食症。其中21名青少年有月经紊乱；其中，14例继发性闭经，7例月经不规律（6例未特定的饮食失调，1例神经性贪食症）。平均而言，神经性厌食青少年的初始体重指数处于第75百分位数；疾病发作1个月后出现继发性闭经；疾病10.2个月时，最低体重为理想体重指数的76.6%（处于第4百分位数）；闭经在24个月时缓解，平均体重恢复到理想体重的93.4%。在伴有月经紊乱的未特定饮食失调患者（n = 10）中，平均初始体重指数处于第85百分位数；疾病14.9个月时，最低体重平均为理想值的97.7%（最低体重指数处于第52百分位数）；疾病1.6年时体重指数稳定；平均体重指数处于第73百分位数。考虑伴有继发性闭经的未特定饮食失调患者（n = 4）；继发性闭经在4个月时出现，疾病12个月时缓解（平均体重指数处于第65百分位数）。
饮食失调组中有三分之一的人有月经紊乱——三分之二表现为闭经。本研究表明，患有饮食失调的女性青少年要解决月经紊乱问题，神经性厌食症患者体重指数需达到第25 - 50百分位数，未特定饮食失调患者需达到第50 - 75百分位数。
