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妊娠巴贝虫病。

Babesiosis in pregnancy.

机构信息

Brigham and Women's Hospital, Boston, Massachusetts.

出版信息

Obstet Gynecol. 2014 Aug;124(2 Pt 2 Suppl 1):419-422. doi: 10.1097/AOG.0000000000000222.

DOI:10.1097/AOG.0000000000000222
PMID:25004307
Abstract

BACKGROUND

Babesiosis is an emerging infectious disease caused by a tick-borne parasite that infects red blood cells. Pregnancy is a relatively immunocompromised state that can underlie severe manifestations of parasitic disease.

CASE

A healthy primiparous patient in the second trimester developed nonspecific symptoms after a tick bite. Evaluation by obstetrics, primary care, and neurology over 4 weeks yielded diagnoses of Lyme disease, upper respiratory infection, migraine, and medication overuse headache. Babesiosis was diagnosed only after she became acutely ill with hemolysis. She was treated with standard antibiotics and had an uncomplicated pregnancy and healthy newborn.

CONCLUSION

Diagnosis of babesiosis in pregnancy requires a high index of suspicion to ensure early treatment and optimal pregnancy outcomes.

摘要

背景

巴贝斯虫病是一种由蜱传播的寄生虫引起的新兴传染病,感染红细胞。妊娠是一种相对免疫功能低下的状态,可能导致寄生虫病的严重表现。

病例

一位健康的初产妇在妊娠中期被蜱叮咬后出现非特异性症状。经过妇产科、初级保健和神经科 4 周的评估,诊断为莱姆病、上呼吸道感染、偏头痛和药物过度使用性头痛。只有在她出现急性溶血性贫血后才诊断出巴贝斯虫病。她接受了标准抗生素治疗,妊娠和新生儿均未出现并发症。

结论

妊娠合并巴贝斯虫病的诊断需要高度怀疑,以确保早期治疗和最佳妊娠结局。

相似文献

1
Babesiosis in pregnancy.妊娠巴贝虫病。
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Human babesiosis: a case study.人类巴贝斯虫病:一项病例研究。
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Congenital Babesiosis After Maternal Infection With Borrelia burgdorferi and Babesia microti.先天性巴贝斯虫病继发于母体感染伯氏疏螺旋体和微小巴贝斯虫。
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[Fever after a tick bite: clinical manifestations and diagnosis of acute tick bite-associated infections in northeastern Switzerland].[蜱虫叮咬后发热:瑞士东北部急性蜱虫叮咬相关感染的临床表现与诊断]
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引用本文的文献

1
Case Report: Lyme Borreliosis and Pregnancy - Our Experience.病例报告:莱姆病与妊娠——我们的经验
Front Med (Lausanne). 2022 Mar 28;9:816868. doi: 10.3389/fmed.2022.816868. eCollection 2022.
2
Impact of Babesia microti infection on the initiation and course of pregnancy in BALB/c mice.感染微小巴贝斯虫对 BALB/c 小鼠妊娠起始和进程的影响。
Parasit Vectors. 2021 Mar 2;14(1):132. doi: 10.1186/s13071-021-04638-0.
3
Babesiosis in Pregnancy: An Imitator of HELLP Syndrome.妊娠期巴贝斯虫病:一种类似HELLP综合征的疾病。
AJP Rep. 2019 Apr;9(2):e147-e152. doi: 10.1055/s-0039-1687873. Epub 2019 Apr 29.
4
Investigating disease severity in an animal model of concurrent babesiosis and Lyme disease.研究同时患有巴贝斯虫病和莱姆病的动物模型中的疾病严重程度。
Int J Parasitol. 2019 Feb;49(2):145-151. doi: 10.1016/j.ijpara.2018.06.006. Epub 2018 Oct 24.
5
Infection Changes Host Spleen Architecture and Is Cleared by a Th1 Immune Response.感染改变宿主脾脏结构并通过Th1免疫反应清除。
Front Microbiol. 2018 Jan 31;9:85. doi: 10.3389/fmicb.2018.00085. eCollection 2018.
6
A novel quantitative PCR detects Babesia infection in patients not identified by currently available non-nucleic acid amplification tests.一种新型定量聚合酶链反应可检测出目前可用的非核酸扩增检测未能识别的患者中的巴贝斯虫感染。
BMC Microbiol. 2017 Jan 14;17(1):16. doi: 10.1186/s12866-017-0929-2.