植入前基因筛查：回到未来。
Preimplantation genetic screening: back to the future.
作者信息
Mastenbroek Sebastiaan, Repping Sjoerd
机构信息
Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Q3-119, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Q3-119, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
出版信息
Hum Reprod. 2014 Sep;29(9):1846-50. doi: 10.1093/humrep/deu163. Epub 2014 Jul 8.
All agree that in hindsight the rapid adoption of preimplantation genetic screening (PGS) using cleavage stage biopsy and fluorescence in situ hybridization (FISH) in routine clinical practice without proper evaluation of (cost-)effectiveness basically resulted in couples paying more money for a less effective treatment. Now, almost 20 years later, we are on the verge of a new era of PGS. But have things really changed or are we simply going back to the future?
所有人都认同，事后看来，在常规临床实践中，未经适当评估（成本 -）效益就迅速采用基于卵裂期活检和荧光原位杂交（FISH）的植入前基因筛查（PGS），基本上导致夫妇们为效果欠佳的治疗支付了更多费用。如今，近20年后，我们正处在PGS新时代的边缘。但情况真的有所改变吗？还是说我们只是在回到过去？
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