Akyigit Abdulvahap, Karlidag Turgut, Sakallioglu Öner, Polat Cahit, Keles Erol
From the *Department of Otorhinolaryngology, Elazig Training and Research Hospital; and †Department of Otorhinolaryngology, Medical Faculty, Firat University, Elazig, Turkey.
J Craniofac Surg. 2014 Jul;25(4):1397-9. doi: 10.1097/SCS.0000000000000876.
Giant cell tumor is a primary bone tumor that usually originates from the epiphysis of the long bones and is rarely seen in the cranial region. Most frequently, the tumor develops in the sphenoid and temporal bones in the middle cranial fossa. Giant cell tumor generally shows diversity with respect to benignity, local invasiveness, and histology. Although surgical excision with negative surgical margin may lead to cure, adjuvant radiotherapy is still debated. The patient was admitted with a humming in the left ear and hearing loss. After radiologic examination, a mass with temporomandibular joint involvement as well as temporal and sphenoid bone localization was detected. The patient was diagnosed with giant cell tumor after a biopsy specimen was taken from the mass extending to the middle ear and destroying the temporomandibular joint. The current study reviewed the patient's clinical features, diagnosis, and treatment in light of the literature.
骨巨细胞瘤是一种原发性骨肿瘤，通常起源于长骨的骨骺，在颅骨区域很少见。最常见的是，肿瘤发生在中颅窝的蝶骨和颞骨。骨巨细胞瘤在良性、局部侵袭性和组织学方面通常表现出多样性。尽管手术切缘阴性的手术切除可能会治愈，但辅助放疗仍存在争议。该患者因左耳嗡嗡作响和听力丧失入院。经放射学检查，发现一个累及颞下颌关节以及颞骨和蝶骨的肿块。从延伸至中耳并破坏颞下颌关节的肿块中取出活检标本后，该患者被诊断为骨巨细胞瘤。本研究根据文献回顾了该患者的临床特征、诊断和治疗情况。
