多核巨骨髓瘤细胞的超微结构：1例报告

Ultrastructure of multinucleated giant myeloma cells: report of one case.

作者信息

Kurabayashi H, Miyawaki S, Murakami H, Nemoto K, Sawamura M, Kubota K, Naruse T, Tsuchiya J

机构信息

Third Department of Medicine, Gunma University School of Medicine, Japan.

出版信息

Am J Hematol. 1989 Aug;31(4):284-5. doi: 10.1002/ajh.2830310414.

DOI:10.1002/ajh.2830310414

PMID:2500853

Abstract

The ultrastructure of multinucleated giant myeloma cells obtained from an IgA kappa myeloma patient was investigated. The characteristic findings were marked nucleocytoplasmic asynchrony, irregular nuclear indentation, branched mitochondria, and Golgi apparatus surrounded by nuclei. The patient died of renal failure only 6 months after diagnosis.

摘要

对一名IgA κ型骨髓瘤患者的多核巨骨髓瘤细胞的超微结构进行了研究。特征性发现为明显的核质不同步、不规则核凹陷、分支状线粒体以及被细胞核包围的高尔基体。该患者在诊断后仅6个月就死于肾衰竭。