Fischer Jason B, Prasad Priya A, Coffin Susan E, Alpern Elizabeth R, Mistry Rakesh D
University of Michigan Medical School, Ann Arbor, MI, USA.
Department of Epidemiology at University of California, San Francisco, CA, USA.
Clin Pediatr (Phila). 2014 Oct;53(12):1174-80. doi: 10.1177/0009922814542608. Epub 2014 Jul 8.
Validated clinical scales, such as the Canadian Acute Respiratory Illness and Flu Scale (CARIFS), have not been used to differentiate influenza (FLU) from other respiratory viruses.
Secondary analysis of a prospective cohort presenting to the emergency department (ED) with an influenza-like infection from 2008 to 2010. Subjects were children aged 0 to 19 years who had a venipuncture and respiratory virus polymerase chain reaction. Demographics and CARIFS items were assessed during the ED visit; comparisons were made between FLU and non-FLU subjects.
The 203 subjects had median age 30.5 months; 61.6% were male. Comorbid conditions (51.2%) were common. FLU was identified in 26.6%, and were older than non-FLU patients (69.7 vs 47.9 months, P = .02). Demographic, household factors, and mean CARIFS score did not differ between FLU (33.7), and non-FLU (32.0) (mean difference 1.6, 95% CI: -2.0 to 5.2) groups.
CARIFS cannot discriminate between FLU and non-FLU infection in ED children with influenza-like infection.
经过验证的临床量表，如加拿大急性呼吸道疾病和流感量表（CARIFS），尚未用于区分流感（FLU）与其他呼吸道病毒。
对2008年至2010年因流感样感染前往急诊科（ED）的前瞻性队列进行二次分析。研究对象为0至19岁进行静脉穿刺和呼吸道病毒聚合酶链反应的儿童。在急诊就诊期间评估人口统计学和CARIFS项目；对流感组和非流感组进行比较。
203名研究对象的中位年龄为30.5个月；61.6%为男性。合并症（51.2%）很常见。流感确诊率为26.6%，流感患者年龄大于非流感患者（69.7个月对47.9个月，P = 0.02）。流感组（33.7）和非流感组（32.0）之间的人口统计学、家庭因素和CARIFS平均得分无差异（平均差异1.6，95%CI：-2.0至5.2）。
在患有流感样感染的急诊儿童中，CARIFS无法区分流感感染和非流感感染。
