Xin Ke-Peng, Du Mao-Lin, Liu Zhi-Yue, Wang Wen-Rui, Qian Yong-Gang, Liu Li, Lv Yun-Fei, Sun Juan
Ke-Peng Xin, Mao-Lin Du, Zhi-Yue Liu, Juan Sun, Department of Public Health, Inner Mongolia Medical University, Hohhot 010110, Inner Mongolia Autonomous Region , China.
World J Gastroenterol. 2014 Jul 7;20(25):8209-14. doi: 10.3748/wjg.v20.i25.8209.
To determine the extent of colorectal cancer (CRC) mortality and the association between demographic characteristics and CRC mortality in Inner Mongolia.
Data were collected from the Death Registry System, maintained by the Inner Mongolia Centers for Disease Control and Prevention, from 2008 to 2012. Deaths were classified according to the International Classification of Disease, 10(th) Revision. Years of life lost, average years of life lost (AYLL), and mortality were calculated over the five years between 2008 and 2012. A conditional logistic regression model was used to analyze the association between marital status, occupational status, education level, area of residence, and the risk of CRC.
The AYLL of CRC was 17.39 years. The average mortality of CRC was 5.6/100000. People living in urban areas and having a higher education level had a significantly higher risk of CRC (OR = 1.74 and 95%CI: 1.29-2.35, P < 0.001 and OR = 2.39, 95%CI: 1.76-3.25, P < 0.001, respectively). People who were employed had a lower risk of CRC (OR = 0.64, 95%CI: 0.48-0.86, P = 0.003). The mortality of CRC was positively correlated with the education level (P < 0.001). No statistically significant association was observed between marital status and CRC risk (P = 0.259).
Living in urban areas, higher education level and unemployment are associated with CRC mortality in Inner Mongolia.
确定内蒙古结直肠癌（CRC）死亡率的程度以及人口统计学特征与CRC死亡率之间的关联。
数据收集自内蒙古疾病预防控制中心维护的2008年至2012年死亡登记系统。死亡按照国际疾病分类第10版进行分类。计算2008年至2012年这五年间的寿命损失年数、平均寿命损失年数（AYLL）和死亡率。采用条件逻辑回归模型分析婚姻状况、职业状况、教育水平、居住地区与CRC风险之间的关联。
CRC的AYLL为17.39年。CRC的平均死亡率为5.6/10万。居住在城市地区且教育水平较高的人群患CRC的风险显著更高（OR = 1.74，95%CI：1.29 - 2.35，P < 0.001；OR = 2.39，95%CI：1.76 - 3.25，P < 0.001）。就业人群患CRC的风险较低（OR = 0.64，95%CI：0.48 - 0.86，P = 0.003）。CRC死亡率与教育水平呈正相关（P < 0.001）。未观察到婚姻状况与CRC风险之间存在统计学显著关联（P = 0.259）。
在内蒙古，居住在城市地区、较高的教育水平和失业与CRC死亡率相关。
