Dyer Anthony, Sadow Peter M, Bracamonte Erika, Gretzer Matthew
Division of Urology, Department of Surgery, The University of Arizona, Tucson, AZ.
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Rev Urol. 2014;16(2):92-4.
Retroperitoneal fibrosis (RPF) is a rare disease characterized by the replacement of normal tissue with fibrosis and/or inflammation. In this case, a 68-year-old man presented with RPF in the pelvis, a rare location for this disease. Biopsies were performed, which showed elevated levels of C-reactive protein, erythrocyte sedimentation rate, and, most importantly, immunoglobulin G4 (IgG4). It has been postulated that IgG4-related sclerosing disease is a systemic disease. Treatment has been successful with systemic corticosteroids.
腹膜后纤维化（RPF）是一种罕见疾病，其特征是正常组织被纤维化和/或炎症所取代。在该病例中，一名68岁男性患有盆腔腹膜后纤维化，这是该疾病的罕见发病部位。进行了活检，结果显示C反应蛋白、红细胞沉降率升高，最重要的是免疫球蛋白G4（IgG4）水平升高。据推测，IgG4相关硬化性疾病是一种全身性疾病。全身使用皮质类固醇治疗已取得成功。
