[儿童伤寒沙门菌和副伤寒沙门菌感染与肠炎沙门菌感染的鉴别]

[Demarcation of infection with Salmonella typhi and S. paratyphi against Salmonella enteritidis in children].

作者信息

Quante S, Kemen C, Höger P H

机构信息

Pädiatrie, Kath. Kinderkrankenhaus Wilhelmstift, Hamburg.

出版信息

Klin Padiatr. 2014 Jul;226(4):238-42. doi: 10.1055/s-0034-1375698. Epub 2014 Jul 10.

DOI:10.1055/s-0034-1375698

PMID:25010129

Abstract

BACKGROUND

Typhoid and paratyphoid infections (STP) are an important differential diagnosis for Salmonella enteritidis infections (NTS). The aim of this study is to carve out clinical differences between both infections.

PATIENTS/METHODS: We retrospectively reviewed all patients admitted to our hospital between 2007 and 2011 with a diagnosis of STP infection. History, clinical course and laboratory findings were compared with age-matched patients suffering from NTS.

RESULTS/DISCUSSION: All patients with an STP-infection showed had a positive travel history (as compared to 11.1% in the NTS group, p<0.01). Salmonella were mostly isolated from blood cultures (n=7/9) in the STP group as compared to 1/16 in the NTS group, where S. enteridis was mainly isolated from faecal cultures (p<0,01). The duration and height of fever as well as the time of hospitalization were significantly longer with STP infections than with NTS infections. Eosinopenia was observed both in STP-(100%) and NTS-infections (77.8%).

CONCLUSION

A positive travel history is crucial to the identification of a STP infection, as well as an eosinopenia.

摘要

背景

伤寒和副伤寒感染（STP）是肠炎沙门氏菌感染（NTS）的重要鉴别诊断。本研究的目的是明确这两种感染之间的临床差异。

患者/方法：我们回顾性分析了2007年至2011年间我院收治的所有诊断为STP感染的患者。将其病史、临床病程和实验室检查结果与年龄匹配的NTS感染患者进行比较。

结果/讨论：所有STP感染患者均有阳性旅行史（NTS组为11.1%，p<0.01）。STP组沙门氏菌大多从血培养中分离出来（n=7/9），而NTS组为1/16，肠炎沙门氏菌主要从粪便培养中分离出来（p<0.01）。STP感染患者的发热持续时间和体温以及住院时间均显著长于NTS感染患者。STP感染（100%）和NTS感染（77.8%）均观察到嗜酸性粒细胞减少。