Suwarto Suhendro, Adlani Hadianti, Nainggolan Leonard, Rumende Cleopas Martin, Soebandrio Amin
1 Senior Lecturer, Division of Tropical and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia.
2 Associate Lecturer, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia.
Trop Doct. 2018 Apr;48(2):124-127. doi: 10.1177/0049475517734118. Epub 2017 Sep 29.
Blood cultures for a definitive diagnosis of typhoid fever takes time and are not routinely available. We thus investigated laboratory parameters to predict Salmonella bacteraemia. We conducted a prospective cohort study in Jakarta, Indonesia. Patients with suspected typhoid fever admitted to hospital from October 2014 to December 2016 were included. Out of 187 individuals, 27 had Salmonella typhi and 12 had S. paratyphi in blood cultures. Absolute eosinopenia, elevated aspartate aminotransferase and elevated C-reactive protein > 40 mg/L were positive predictors.
通过血培养来明确诊断伤寒热需要时间,而且并非常规可用。因此,我们研究了用于预测沙门氏菌血症的实验室指标。我们在印度尼西亚雅加达进行了一项前瞻性队列研究。纳入了2014年10月至2016年12月期间因疑似伤寒热入院的患者。在187名个体中,血培养显示27人感染伤寒杆菌,12人感染副伤寒杆菌。绝对嗜酸性粒细胞减少、天冬氨酸转氨酶升高以及C反应蛋白升高>40mg/L是阳性预测指标。