Caglar M K, Tolboom J
Department of Pediatrics, University Hospital Nijmegen, The Netherlands.
Helv Paediatr Acta. 1989 Jun;43(5-6):483-6.
An infant with superior vena cava syndrome due to thrombus formation in the superior vena cava, sourced from a central venous line, was treated with urokinase. It was used in a loading dose of 250,000 units/1.73 m2/15 min, followed by continuous infusion of 125,000 units/1.73 m2/h for three days. After two days of urokinase treatment, the clinical signs of superior vena cava syndrome completely disappeared. No bleeding complication was observed.
一名因上腔静脉内血栓形成导致上腔静脉综合征的婴儿,血栓源于中心静脉导管,接受了尿激酶治疗。尿激酶的负荷剂量为250,000单位/1.73平方米/15分钟,随后以125,000单位/1.73平方米/小时的速度持续输注三天。尿激酶治疗两天后,上腔静脉综合征的临床症状完全消失。未观察到出血并发症。