Uesugi H, Azuumi Y, Saigenji K, Okabe H, Mieno H, Motoori T
Dept. of Int. Med., Kitasato Univ. East Hospital.
Gan No Rinsho. 1989 Jul;35(8):963-9.
On June 2, 1988, a 63-year-old male visited Kitasato University East Hospital because of body weight loss. After an upper GI series and endoscopic examination the patient was diagnosed as having an advanced gastric cancer (Borrmann's type 2) that occupied the anterior wall of the mid portion of the stomach. Endoscopic biopsied specimens showed a poorly differentiated adenocarcinoma, histologically. Thus, the patient was administered UFT (600 mg/day) for preoperative chemotherapy for 3 weeks, and then underwent surgery on July 7, 1988. In a resected specimen, the cancerous lesion was found to have reduced in size and, macroscopically, had changed to a more flat type. Further, on histological examination, no cancerous cell were found in the primary lesion or in the regional lymph nodes in the resected specimen. Thus we report this case as representing a complete to UFT chemotherapy.
1988年6月2日，一名63岁男性因体重减轻就诊于北里大学东医院。经过上消化道造影和内镜检查，患者被诊断为进展期胃癌（Borrmann 2型），占据胃中部前壁。内镜活检标本组织学显示为低分化腺癌。因此，患者接受了UFT（600毫克/天）术前化疗3周，然后于1988年7月7日接受手术。在切除标本中，癌灶体积缩小，肉眼观察变为更扁平的类型。此外，组织学检查发现切除标本的原发灶及区域淋巴结均未发现癌细胞。因此，我们报告此病例为UFT化疗完全缓解。
